The effects of the composition and dispersion of the oil phase on the antigenicity of the associated inactivated vaccine against chicken infectious bronchitis, Newcastle disease, and egg drop syndrome-76
Ptitsevodstvo
; 12:64-68, 2021.
Article
in Russian
| CAB Abstracts | ID: covidwho-1841843
ABSTRACT
The antigenicity of three inactivated emulsified associated vaccines against viruses of chicken infectious bronchitis (IB), Newcastle disease (ND), and egg drop syndrome-76 (EDS-76) based on the oil adjuvant ISA-15 (O/W) was comparatively studied (1) reference vaccine (IB+ND+EDS-76/ISA-15);(2) experimental vaccine (IB+NB+EDS-76/ISA-15-Nano) with a nanoscale-dispersed oil phase obtained by the use of a high-pressure homogenizer;(3) similar nano-scale vaccine (IB+NB+EDS-76+CoAA/ ISA-15-Nano) additionally supplemented with a copolymer of acrylic acid (CoAA). The in vivo tests of the vaccines on the chicks evidenced that both nano-scale vaccines enhanced the immune response in vaccinated chicks as compared to the reference vaccine and that supplementation with CoAA resulted in the highest postvaccinal antibody titers.
Animal Immunology [LL650]; Prion, Viral, Bacterial and Fungal Pathogens of Animals [LL821]; Host Resistance and Immunity [HH600]; Egg Producing Animals [LL130]; vaccines; immune response; adjuvants; animal diseases; antibodies; antigens; chicks; fowl diseases; inactivated vaccines; poultry; poultry diseases; emulsification; disease prevention; disease control; egg drop syndrome; vaccination; avian infectious bronchitis; Newcastle disease virus; fowls; Infectious bronchitis virus; birds; Avulavirus; Paramyxovirinae; Paramyxoviridae; Mononegavirales; negative-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; viruses; Gallus gallus; Gallus; Phasianidae; Galliformes; vertebrates; Chordata; animals; eukaryotes; Avian coronavirus; Gammacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; immunity reactions; immunological reactions; antigenicity; immunogens; chickens; killed vaccines; IBV infection; domesticated birds
Full text:
Available
Collection:
Databases of international organizations
Database:
CAB Abstracts
Type of study:
Experimental Studies
Topics:
Vaccines
Language:
Russian
Journal:
Ptitsevodstvo
Year:
2021
Document Type:
Article
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