Severe Immune Thrombocytopenia after COVID-19 Vaccination: Two Case Reports and a Literature Review.
Intern Med
; 61(10): 1581-1585, 2022 May 15.
Article
in English
| MEDLINE | ID: covidwho-1847020
ABSTRACT
We herein report two cases of coronavirus disease 2019 (COVID-19) vaccine-induced immune thrombocytopenia (ITP). A 69-year-old Japanese man developed severe thrombocytopenia after COVID-19 vaccination. He had oral bleeding and hemoptysis but no thrombotic symptoms. He improved rapidly with oral prednisolone therapy. A 34-year-old Japanese woman had generalized purpura after COVID-19 vaccination. Her platelet count improved rapidly after treatment with prednisolone and eltrombopag. The occurrence of two cases of ITP after COVID-19 vaccination at a single institution suggests that there could be more such undiagnosed cases, especially cases of mild secondary ITP.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Thrombocytopenia
/
Purpura, Thrombocytopenic, Idiopathic
/
COVID-19
Type of study:
Case report
/
Diagnostic study
/
Reviews
Topics:
Vaccines
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
Intern Med
Journal subject:
Internal Medicine
Year:
2022
Document Type:
Article
Affiliation country:
Internalmedicine.9177-21
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