Performance Evaluation of a Rapid Antigen Test (RAT) during Omicron Pandemic Wave in Greece, Conducted by Different Personnel, and Comparison with Performance in Previous Wave (Alpha Variant) Period.
Diagnostics (Basel)
; 12(5)2022 Apr 21.
Article
in English
| MEDLINE | ID: covidwho-1847278
ABSTRACT
Due to the prevailing ambiguity regarding the performance of rapid antigen tests (RATs) for B.1.1.529 (Omicron) variant diagnosis, a commercial RAT was evaluated in the emergency ward of a general hospital in Larissa, Central Greece. The sampling and the evaluation were repeated twice by different personnel. Discordance between the two samplings was observed regarding the sensitivity (47.5%, 95% CI 39.0-56.1 vs. 78.6%, 95% CI 69.1-86.2) and specificity (93.8%, 95% CI 86.0-97.9 vs. 100.0%, 95% CI 93.3-100.0) of the RAT. Furthermore, the test displayed slightly lower sensitivity (78.6% vs. 85.5%, 95% CI 79.1-90.5) compared to its initial evaluation that was conducted by our team when the B.1.1.7 (Alpha) variant was dominant.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Diagnostic study
/
Experimental Studies
Topics:
Variants
Language:
English
Year:
2022
Document Type:
Article
Affiliation country:
Diagnostics12051048
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