Construction of Information Bank of Chemical Components in Isatidis Radix
Chinese Pharmaceutical Journal
; 57(6):428-452, 2022.
Article
in Chinese
| Scopus | ID: covidwho-1847717
ABSTRACT
OBJECTIVE:
Isatidis Radix is the dried root of Isatis indigotica Fortune of Cruciferae. As a representative traditional Chinese medicine for heat-clearing and detoxification, Isatidis Radix and its preparations are widely used in the prevention and treatment of all kinds of colds and have played an active role in the prevention and treatment of SARS, H1N1 and COVID-19. Although the chemical ingredient of Isatidis Radix has been studied deeply, there is no information bank, website or literature that can comprehensively query the information of all compounds at home and abroad, which is not conducive to the development of related research. So establishment of the chemical composition information bank is in need.METHODS:
According to the category of chemical ingredients, the Chinese and English names, molecular formulas, exact molecular weights, structural formulas and references of nearly 400 chemical components in Isatidis Radix were comprehensively sorted out, and the chemical composition information bank of Isatidis Radix was constructed.RESULTS:
By September 2020, a total of 392 compounds in 17 categories had been extracted, isolated and identified from Isatidis Radix. CONCLUSIONT The established chemical composition information bank can provide the basis for the separation and identification of chemical components, quality control, material basis mining, network pharmacology research and so on. Copyright 2022 by the Chinese Pharmaceutical Association.
Full text:
Available
Collection:
Databases of international organizations
Database:
Scopus
Language:
Chinese
Journal:
Chinese Pharmaceutical Journal
Year:
2022
Document Type:
Article
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