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Outcomes of Ongoing Living and Cadaveric Kidney Transplantations within the COVID-19 Pandemic in Two Referral Centers.
Simforoosh, Naser; Eslami, Atefe; Mohammadian Roshan, Yaghub; Ali Askari, Majeed; Masoumi, Navid; Vaezjalali, Maryam; Ziaeefar, Pardis; Kashi, Amir Hossein.
  • Simforoosh N; Urology and Nephrology Research Center (UNRC), Shahid Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran. simforoosh@iutc.org.ir.
  • Eslami A; Urology and Nephrology Research Center (UNRC), Shahid Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran. atf.esl70@gmail.com.
  • Mohammadian Roshan Y; Urology and Nephrology Research Center (UNRC), Shahid Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran. yaghoobmohamadian.alpha@yahoo.com.
  • Ali Askari M; Department of Urology, Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. majeed_asgari@yahoo.com.
  • Masoumi N; Department of Urology, Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. nmasoumig@gmail.com.
  • Vaezjalali M; Department of Microbiology, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran. maryam.Vaezjalali@gmail.com.
  • Ziaeefar P; Urology and Nephrology Research Center (UNRC), Shahid Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran.
  • Kashi AH; Urology and Nephrology Research Center (UNRC), Shahid Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran. ahkashi@gmail.com.
Urol J ; 2022 02 08.
Article in English | MEDLINE | ID: covidwho-20242982
ABSTRACT

PURPOSE:

To present the early to midterm experience of two referral kidney transplantation centers with living and deceased kidney transplantations that were performed within the COVID-19 pandemic. MATERIALS AND

METHODS:

All cases performed in two referral centers in Iran within the COVID-19 pandemic were investigated. Transplantations were performed from May 2020 to February 2021. The protocol for screening included nasopharyngeal RT-PCR with chest CT scan for living and deceased transplantations in center A and RT-PCR for living transplantations and chest CT scan for deceased transplantations in center B. Patients were followed for 14-26 months after transplantation regarding COVID-19 infection and its outcomes in case of infection.

RESULTS:

103 kidney transplantations were performed during the study period including 54 (52.4%) living and 49 (47.6%) deceased kidney transplantations. Twenty-four recipients (23.3%) and a living donor (1%) were infected with COVID-19. The severity of COVID-19 infection was mild, moderate, severe, and critical in 16 (66.6%), 4 (16.6%), 2 (8.4%), and 2 patients (8.4%), respectively. Two mortalities were observed within transplantation recipients with COVID-19 infection (1.9%). 87.5% (7/8) COVID-19 infections in center B were observed in recipients of deceased transplantations who were screened only by chest CT scan.

CONCLUSION:

The results of this study indicate a low frequency of COVID-19 mortality (1.9% for the whole cohort and 8.3% within COVID-19 infected patients) for recipients of living and deceased kidney transplantation that were performed within the COVID-19 pandemic. The above findings highlight for the first time in a large study the probability of living kidney transplantation during the COVID-19 pandemic in case strict screening of donors and recipients and close supervision of operating rooms and wards are implemented. We further hopothetize the inadequacy of chest CT scan for screening of COVID-19 in kidney transplantation surgery candidates.

Full text: Available Collection: International databases Database: MEDLINE Type of study: Cohort study / Observational study / Prognostic study Language: English Journal subject: Urology Year: 2022 Document Type: Article Affiliation country: Uj.v18i.6930

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Cohort study / Observational study / Prognostic study Language: English Journal subject: Urology Year: 2022 Document Type: Article Affiliation country: Uj.v18i.6930