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VacSIM: Learning effective strategies for COVID-19 vaccine distribution using reinforcement learning.
Awasthi, Raghav; Guliani, Keerat Kaur; Khan, Saif Ahmad; Vashishtha, Aniket; Gill, Mehrab Singh; Bhatt, Arshita; Nagori, Aditya; Gupta, Aniket; Kumaraguru, Ponnurangam; Sethi, Tavpritesh.
  • Awasthi R; Indraprastha Institute of Information Technology Delhi, India.
  • Guliani KK; Indian Institute of Technology Roorkee, India.
  • Khan SA; Indraprastha Institute of Information Technology Delhi, India.
  • Vashishtha A; Maharaja Surajmal Institute of Technology, New Delhi, India.
  • Gill MS; Indraprastha Institute of Information Technology Delhi, India.
  • Bhatt A; Bhagwan Parshuram Institute of Technology, New Delhi, India.
  • Nagori A; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
  • Gupta A; Indraprastha Institute of Information Technology Delhi, India.
  • Kumaraguru P; Indraprastha Institute of Information Technology Delhi, India.
  • Sethi T; Indraprastha Institute of Information Technology Delhi, India.
Intell Based Med ; 6: 100060, 2022.
Article in English | MEDLINE | ID: covidwho-1851179
ABSTRACT
A COVID-19 vaccine is our best bet for mitigating the ongoing onslaught of the pandemic. However, vaccine is also expected to be a limited resource. An optimal allocation strategy, especially in countries with access inequities and temporal separation of hot-spots, might be an effective way of halting the disease spread. We approach this problem by proposing a novel pipeline VacSIM that dovetails Deep Reinforcement Learning models into a Contextual Bandits approach for optimizing the distribution of COVID-19 vaccine. Whereas the Reinforcement Learning models suggest better actions and rewards, Contextual Bandits allow online modifications that may need to be implemented on a day-to-day basis in the real world scenario. We evaluate this framework against a naive allocation approach of distributing vaccine proportional to the incidence of COVID-19 cases in five different States across India (Assam, Delhi, Jharkhand, Maharashtra and Nagaland) and demonstrate up to 9039 potential infections prevented and a significant increase in the efficacy of limiting the spread over a period of 45 days through the VacSIM approach. Our models and the platform are extensible to all states of India and potentially across the globe. We also propose novel evaluation strategies including standard compartmental model-based projections and a causality-preserving evaluation of our model. Since all models carry assumptions that may need to be tested in various contexts, we open source our model VacSIM and contribute a new reinforcement learning environment compatible with OpenAI gym to make it extensible for real-world applications across the globe.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study Topics: Vaccines Language: English Journal: Intell Based Med Year: 2022 Document Type: Article Affiliation country: J.ibmed.2022.100060

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study Topics: Vaccines Language: English Journal: Intell Based Med Year: 2022 Document Type: Article Affiliation country: J.ibmed.2022.100060