Factors associated with development and persistence of post-COVID conditions: A cross-sectional study.
J Infect Chemother
; 28(9): 1242-1248, 2022 Sep.
Article
in English
| MEDLINE | ID: covidwho-1851526
ABSTRACT
INTRODUCTION:
The post-COVID condition has become a social concern. Although the patient characteristics associated with the development of this condition are partially known, those associated with its persistence have not been identified.METHODS:
We conducted a cross-sectional questionnaire-based survey among patients who had recovered from COVID-19 and visited the National Center for Global Health and Medicine between February 2021 and March 2021. Demographic and clinical data, and data regarding the presence and duration of post-COVID conditions were obtained. We identified factors associated with the development and persistence of post-COVID conditions using multivariate logistic and linear regression analyses, respectively.RESULTS:
We analyzed 457 of 526 responses (response rate, 86.9%). The median patient age was 47 years. Of these, 378 patients (84.4%) had mild disease in the acute phase. The number of patients with symptoms at 6 and 12 months after onset or diagnosis was 120 (26.3%) and 40 (8.8%), respectively. Women were at risk of developing fatigue (odds ratio [OR] 2.03, 95% confidence interval [CI] 1.31-3.14), dysosmia (OR 1.91, 95%CI 1.24-2.93), dysgeusia (OR 1.56, 95%CI 1.02-2.39), hair loss (OR 3.00, 95%CI 1.77-5.09), and persistence of any symptoms (coefficient 38.0, 95%CI 13.3-62.8). Younger age and low body mass index were factors for developing dysosmia (OR 0.96, 95%CI 0.94-0.98 and OR 0.94, 95%CI 0.89-0.99, respectively) and dysgeusia (OR 0.98, 95%CI 0.96-1.00 and OR 0.93, 95%CI 0.88-0.98, respectively).CONCLUSION:
We identified factors involved in the development and persistence of post-COVID conditions. Many patients, even those with mild conditions, experience long-term residual symptoms.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
/
Olfaction Disorders
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Topics:
Long Covid
Limits:
Female
/
Humans
/
Middle aged
Language:
English
Journal:
J Infect Chemother
Journal subject:
Microbiology
/
Drug Therapy
Year:
2022
Document Type:
Article
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