Kikuchi-Fujimoto disease can present as delayed lymphadenopathy after COVID-19 vaccination.
Hum Vaccin Immunother
; 18(5): 2071080, 2022 11 30.
Article
in English
| MEDLINE | ID: covidwho-1852828
ABSTRACT
Following COVID-19 vaccination, ipsilateral axillary and cervical lymphadenopathy may occur, called vaccine-related hypermetabolic lymphadenopathy, which is considered reactive lymphadenopathy. We report here a case of Kikuchi-Fujimoto disease, which occurred three months after vaccination with COVID-19 vaccine. The patient had cervical and axillary lymph node enlargement and a short-term fever that resolved spontaneously after the first and second vaccines. On the 90th day after the first vaccination, the patient developed a high fever and pathologically diagnosed necrotizing lymphadenitis in the axilla, which was diagnosed as Kikuchi-Fujimoto disease. Gallium scintigraphy showed localized swelling and strong uptake in the ipsilateral axilla. It implies the possibility of Kikuchi-Fujimoto Disease in axillary drainage lymph nodes in association with COVID-19 vaccine. Although only a few cases have been reported so far, this case is novel because of its later onset and diagnosis based on pathological and gallium scintigraphy imaging findings.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Histiocytic Necrotizing Lymphadenitis
/
Lymphadenopathy
/
Gallium
/
COVID-19 Vaccines
/
COVID-19
Type of study:
Case report
/
Diagnostic study
/
Observational study
Topics:
Long Covid
/
Vaccines
Limits:
Humans
Language:
English
Journal:
Hum Vaccin Immunother
Year:
2022
Document Type:
Article
Affiliation country:
21645515.2022.2071080
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