The Role of Nanotechnology in Antiviral Regime: An Overview
Nano LIFE
; 12(1), 2022.
Article
in English
| EMBASE | ID: covidwho-1854417
ABSTRACT
Nanomedicine or nanotechnology exhibits outstanding features to challenge severe health issues including pathogenic viral infections, the most culpable invaders in the present situation. The perpetual mutational pattern in viruses topped with raising resistance to drug epitomizes the current situation as a trigger to explore nanotech platforms in antiviral therapies. Referring to novel physicochemical features of nanomaterials associated with effective drug delivery, it is viewed as an ideal strategy for treatment of viral infections. The coronavirus induced pathogenesis, including MERS, SARS and SARS-CoV-2 infections, has triggered alarming and highly dangerous precedents against existence of humans. Applications of nanotechnology can serve a new direction for disinfection or treatment of viruses. Presently, various types of nanomaterials, such as nanogels, nanospheres, nanocapsules, liposomes, nanoparticles and many others, that have been investigated in vivo and in vitro for successful drug delivery, vaccination, diagnostic assay and device development with anticipation to be translated in advanced clinical practices, need a collective relook. This paper intents to contribute insightful critique of current studies on the efficacy of nanoplatforms as drug transporter, diagnostic tool and vaccine candidate against pathogenic viruses counting the highly pathogenic and incurable "coronaviruses".
NCT04368988; immunochromatographic assay kit; immunosensor; nanodevice; aciclovir; amantadine; antisense oligonucleotide; antivirus agent; atazanavir; beta interferon; chitosan nanoparticle; copper nanoparticle; dendrimer; dexamethasone; dodecyl sulfate sodium; efavirenz; elasomeran; enfuvirtide; gamma interferon; ganciclovir; gold nanoparticle; hepatitis A vaccine; Human immunodeficiency virus vaccine; indinavir; inflaxal; influenza vaccine; lamivudine; liposome; maraviroc; metal oxide nanoparticle; nanocapsule; nanocomposite; nanosphere; oseltamivir; polymer nanoparticle; quantum dot; raltegravir; remdesivir; saquinavir; silver nanoparticle; surfactant; zanamivir; zidovudine; antiviral therapy; article; biocompatibility; colorimetry; coronavirus disease 2019; diagnosis; double-stranded DNA reverse transcribing virus; double-stranded DNA virus; double-stranded RNA virus; human; micelle; nanotechnology; negative-strand RNA virus; nonhuman; real time reverse transcription polymerase chain reaction; SARS coronavirus; single-stranded DNA virus; single-stranded RNA reverse transcribing virus; single-stranded RNA virus; dermavir; epaxal; influvac
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Language:
English
Journal:
Nano LIFE
Year:
2022
Document Type:
Article
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