Vive la Résistance: T-cell Immunity in the Protection against SARS-CoV-2 Infection.
Cancer Discov
; 12(4): 892-894, 2022 04 01.
Article
in English
| MEDLINE | ID: covidwho-1854525
ABSTRACT
SUMMARY:
Fahrner and colleagues investigated the immune response of patients with cancer and cancer-free individuals to SARS-CoV-2 and found that a propensity toward an IL5-predominant Th2/Tc2 response was predictive of susceptibility to infection. The results of this study also suggest that a cellular response against the Spike 1 protein receptor binding domain (S1-RBD) region of the SARS-CoV-2 proteome contributes to protection and that mutations in this region may drive viral evolution and immune escape. See related article by Fahrner et al., p. 958 (8).
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Cancer Discov
Year:
2022
Document Type:
Article
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