Role of Neutrophils on the Ocular Surface.
Int J Mol Sci
; 22(19)2021 Sep 27.
Article
in English
| MEDLINE | ID: covidwho-1855649
ABSTRACT
The ocular surface is a gateway that contacts the outside and receives stimulation from the outside. The corneal innate immune system is composed of many types of cells, including epithelial cells, fibroblasts, natural killer cells, macrophages, neutrophils, dendritic cells, mast cells, basophils, eosinophils, mucin, and lysozyme. Neutrophil infiltration and degranulation occur on the ocular surface. Degranulation, neutrophil extracellular traps formation, called NETosis, and autophagy in neutrophils are involved in the pathogenesis of ocular surface diseases. It is necessary to understand the role of neutrophils on the ocular surface. Furthermore, there is a need for research on therapeutic agents targeting neutrophils and neutrophil extracellular trap formation for ocular surface diseases.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Cell Degranulation
/
Cornea
/
Neutrophil Infiltration
/
Eye Diseases
/
Extracellular Traps
/
Neutrophils
Type of study:
Reviews
Limits:
Humans
Language:
English
Year:
2021
Document Type:
Article
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