Incidence of acute kidney injury in hospitalized COVID-19 patients from a tertiary care hospital
Lung India
; 39(SUPPL 1):S147-S148, 2022.
Article
in English
| EMBASE | ID: covidwho-1856947
ABSTRACT
Background:
Novel coronavirus disease caused by SARSCoV- 2, primarily manifest as an acute respiratory illness;however, it can also affect multiple organs, such as kidneys, heart, digestive tract, hematological and the nervous system. Acute kidney injury (AKI) has been reported in up to 25% of critically-ill patients with SARS-CoV-2 infection, especially in those with underlying comorbidities. Aim of the Study To study the incidence of Acute Kidney Injury in hospitalized COVID-19 patients.Methods:
This is a retrospective study conducted in Dept of Respiratory Medicine, KIMS Hospital and Research Centre, Bengaluru. A total of 1000 COVID patients were taken in the order of their admission to the hospital from Jan -May 2021. Blood urea and serum creatinine levels at the time of admission was collected. Ethical clearance was obtained from the institutional ethical committee.Results:
Statistically significant correlation was found between the incidence of AKI and the COVID-19 disease severity and mortality. Correlation by Pearson 2 tailed shows a positive correlation with a value of 0.713. Patients with renal involvement had higher overall mortality compared with patients without renal involvement. Adverse short-term outcomes of renal involvement were associated with severity of COVID-19 pneumoniaConclusion:
AKI could be used as a clinical characteristic in severity classification and risk stratification. Further investigation of the underlying mechanism of renal disease in COVID-19 would be needed to clarify possible therapeutic targets.
acute kidney failure; adult; all cause mortality; clinical feature; comorbidity; conference abstract; controlled study; coronavirus disease 2019; creatinine blood level; critically ill patient; female; human; human tissue; incidence; kidney disease; major clinical study; male; mortality; outcome assessment; retrospective study; tertiary care center; urea blood level
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Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Observational study
Language:
English
Journal:
Lung India
Year:
2022
Document Type:
Article
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