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Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020.
Haveri, Anu; Smura, Teemu; Kuivanen, Suvi; Österlund, Pamela; Hepojoki, Jussi; Ikonen, Niina; Pitkäpaasi, Marjaana; Blomqvist, Soile; Rönkkö, Esa; Kantele, Anu; Strandin, Tomas; Kallio-Kokko, Hannimari; Mannonen, Laura; Lappalainen, Maija; Broas, Markku; Jiang, Miao; Siira, Lotta; Salminen, Mika; Puumalainen, Taneli; Sane, Jussi; Melin, Merit; Vapalahti, Olli; Savolainen-Kopra, Carita.
  • Haveri A; Department of Health Security, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
  • Smura T; University of Helsinki, Medicum, Department of Virology, Helsinki, Finland.
  • Kuivanen S; University of Helsinki, Medicum, Department of Virology, Helsinki, Finland.
  • Österlund P; Department of Health Security, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
  • Hepojoki J; University of Helsinki, Medicum, Department of Virology, Helsinki, Finland.
  • Ikonen N; Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zürich, Zürich, Switzerland.
  • Pitkäpaasi M; Department of Health Security, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
  • Blomqvist S; Department of Health Security, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
  • Rönkkö E; Department of Health Security, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
  • Kantele A; Department of Health Security, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
  • Strandin T; Inflammation Center, Infectious Diseases, Helsinki University Hospital (HUSLAB) and University of Helsinki, Helsinki, Finland.
  • Kallio-Kokko H; University of Helsinki, Medicum, Department of Virology, Helsinki, Finland.
  • Mannonen L; Department of Virology and Immunology, Helsinki University Hospital (HUSLAB) and University of Helsinki, Helsinki, Finland.
  • Lappalainen M; Department of Virology and Immunology, Helsinki University Hospital (HUSLAB) and University of Helsinki, Helsinki, Finland.
  • Broas M; Department of Virology and Immunology, Helsinki University Hospital (HUSLAB) and University of Helsinki, Helsinki, Finland.
  • Jiang M; Infection-Hospital Hygiene Unit, Lapland Central Hospital, Rovaniemi, Finland.
  • Siira L; Department of Health Security, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
  • Salminen M; Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.
  • Puumalainen T; Department of Health Security, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
  • Sane J; Department of Health Security, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
  • Melin M; Department of Health Security, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
  • Vapalahti O; Department of Health Security, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
  • Savolainen-Kopra C; Department of Health Security, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
Euro Surveill ; 25(11)2020 03.
Article in English | MEDLINE | ID: covidwho-18570
ABSTRACT
The first case of coronavirus disease (COVID-19) in Finland was confirmed on 29 January 2020. No secondary cases were detected. We describe the clinical picture and laboratory findings 3-23 days since the first symptoms. The SARS-CoV-2/Finland/1/2020 virus strain was isolated, the genome showing a single nucleotide substitution to the reference strain from Wuhan. Neutralising antibody response appeared within 9 days along with specific IgM and IgG response, targeting particularly nucleocapsid and spike proteins.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Travel / Contact Tracing / Coronavirus Infections / Coronavirus / Severe Acute Respiratory Syndrome / Severe acute respiratory syndrome-related coronavirus / Pandemics Type of study: Case report / Diagnostic study / Prognostic study Limits: Adult / Female / Humans Country/Region as subject: Asia / Europa Language: English Journal subject: Communicable Diseases Year: 2020 Document Type: Article Affiliation country: 1560-7917.Es.2020.25.11.2000266

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Travel / Contact Tracing / Coronavirus Infections / Coronavirus / Severe Acute Respiratory Syndrome / Severe acute respiratory syndrome-related coronavirus / Pandemics Type of study: Case report / Diagnostic study / Prognostic study Limits: Adult / Female / Humans Country/Region as subject: Asia / Europa Language: English Journal subject: Communicable Diseases Year: 2020 Document Type: Article Affiliation country: 1560-7917.Es.2020.25.11.2000266