Hematological and biochemical changes associated with COVID 19

ABSTRACT

Introduction: Severe acute respiratory syndrome coronavirus causing coronavirus disease 2019 has rapidly evolved from an epidemic outbreak in Wuhan, China, into a pandemic affecting more than 1 million individuals worldwide. It is associated with leucopenia , thrombocytopenia, deranged LFT and elevated inflammatory markers including CRP , D-DIMER , LDH and ferritin Aims and Objectives: 1. To find the proportion of hematopoietic and biochemical changes in category A, B, C patients 2. To find the proportion of inflammatory markers elevated in category C patients. Methods: A cross sectional study among 500 COVID 19 patients who were diagnosed with RT PCR admitted in MES medical college hospital. Routine investigations along with inflammatory markers are analysed. Results: In the hemogram, 38 % had leukocytosis , 8 % had leucopenia, 7 % had thrombocytopenia , 85% had elevated CRP, 61 % had elevated D- dimer, 37 % had elevated Ferritin and 24 % had elevated LDH. Conclusion: Analyzing the inflammato.y markers, hematological and biochemical derangements, and how they correlate with disease severity.