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Cardiac Temponade post COVID-19 vaccination due to reactivation of tuberculosis
Lung India ; 39(SUPPL 1):S138, 2022.
Article in English | EMBASE | ID: covidwho-1857345
ABSTRACT

Background:

35yrs female, without comorbidities hospitalised in emergency in icu due to sudden severe breathlessness and chest pain, fever, weakness, cold, throat pain, vomiiting of 4 to 5 days duration. Case Study H/o 1st dose covid vaccination received 4 to 5 days ago. Latest COVID RT-PCR negative. Patient required o2 support as her Spo2 on admission was 87%.All necessary lab done. 2DECHO done by cardiologist s/o moderate pericardial effusion causing temponade, also dilated RA/ RV, RV dysfunction, septal buging s/o effussion/constrictive pericarditis. Hence emergency pericardiocentesis was done under fluroscopic guidence. 500ml pale yellow fluid aspirated and pigtail was placed. Fluid was sent for testing. It showed on Gene Xpert detection of mycobacterium tuberculosis and no resistance to rifampicin. Pulmonary embolism and other systemic causes of pericardial effusion ruled out. Patient gave history of Miliary tuberculosis and completed treatment 1 month ago with HRCT chest after treatment completed showing normal lung parenchyama. All symptoms started on the day of vaccination in evening. She also had associated bilateral moderate pleural effusion L>>R. Left sided pleural fluid tapping done and sent for examination. Pt was started on 1st line anti-TB drugs along with diuretics, steroids. She responded well to treatment. Subsequent follow up 2DECHO screening and CXR showed resolution of effusion. Pigtail pericardial catheter removed, O2 tapered off and patient discharged home. Called for follow up after 1 week for 2DECHO screening. Pericardial fluid TB liquid culture was sent which showed no growth after 8 weeks.

Discussion:

Reactivation of tuberculosis doesn't occur in all cases who has received covid-19 vaccination but we noted in 1 of our case.

Conclusion:

Reactivation of tuberculosis causing life threatning complication post COVID-19 vaccination.
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Collection: Databases of international organizations Database: EMBASE Topics: Long Covid / Vaccines Language: English Journal: Lung India Year: 2022 Document Type: Article

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Collection: Databases of international organizations Database: EMBASE Topics: Long Covid / Vaccines Language: English Journal: Lung India Year: 2022 Document Type: Article