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Performance of the Sofia SARS-CoV-2 Rapid Antigen Test in Symptomatic and Asymptomatic Pediatric Patients.
Freeman, Megan Culler; Freeman, Tanner J; Iagnemma, Jennifer; Rasmussen, Jayne; Heidenreich, Kelly; Wells, Alan; Hoberman, Alejandro; Mitchell, Stephanie L.
  • Freeman MC; Department of Pediatrics, Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Freeman TJ; Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Iagnemma J; Children's Community Pediatrics, Pittsburgh, Pennsylvania, USA.
  • Rasmussen J; Clinical Microbiology Laboratory, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Heidenreich K; Children's Community Pediatrics, Pittsburgh, Pennsylvania, USA.
  • Wells A; Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Hoberman A; Department of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Mitchell SL; Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
J Pediatric Infect Dis Soc ; 11(9): 417-421, 2022 Sep 29.
Article in English | MEDLINE | ID: covidwho-1860881
ABSTRACT
The sensitivity and specificity of SARS-CoV-2 antigen tests have not been widely assessed in children. We evaluated children presenting to outpatient care with Quidel Sofia SARS-CoV-2 antigen test (Sofia-Ag-RDT) compared against Cepheid Xpert Xpress SARS-CoV-2/Flu/RSV reverse transcriptase-polymerase chain reaction test from November 2020 to April 2021. Sofia-Ag-RDT had the highest sensitivity in symptomatic (82%; 95% confidence interval, 68%-91%) children.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Diagnostic study / Experimental Studies Limits: Child / Humans Language: English Journal: J Pediatric Infect Dis Soc Year: 2022 Document Type: Article Affiliation country: Jpids

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Diagnostic study / Experimental Studies Limits: Child / Humans Language: English Journal: J Pediatric Infect Dis Soc Year: 2022 Document Type: Article Affiliation country: Jpids