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Twin peaks: The Omicron SARS-CoV-2 BA.1 and BA.2 epidemics in England.
Elliott, Paul; Eales, Oliver; Steyn, Nicholas; Tang, David; Bodinier, Barbara; Wang, Haowei; Elliott, Joshua; Whitaker, Matthew; Atchison, Christina; Diggle, Peter J; Page, Andrew J; Trotter, Alexander J; Ashby, Deborah; Barclay, Wendy; Taylor, Graham; Ward, Helen; Darzi, Ara; Cooke, Graham S; Donnelly, Christl A; Chadeau-Hyam, Marc.
  • Elliott P; School of Public Health, Imperial College London, London, UK.
  • Eales O; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
  • Steyn N; Imperial College Healthcare NHS Trust, London, UK.
  • Tang D; National Institute for Health Research Imperial Biomedical Research Centre, London, UK.
  • Bodinier B; Health Data Research (HDR) UK, Imperial College London, London, UK.
  • Wang H; UK Dementia Research Institute, Imperial College London, London, UK.
  • Elliott J; School of Public Health, Imperial College London, London, UK.
  • Whitaker M; MRC Centre for Global infectious Disease Analysis and Jameel Institute, Imperial College London, London, UK.
  • Atchison C; Department of Statistics, University of Oxford, Oxford, UK.
  • Diggle PJ; Department of Mathematics, Imperial College London, London, UK.
  • Page AJ; School of Public Health, Imperial College London, London, UK.
  • Trotter AJ; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
  • Ashby D; School of Public Health, Imperial College London, London, UK.
  • Barclay W; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
  • Taylor G; School of Public Health, Imperial College London, London, UK.
  • Ward H; MRC Centre for Global infectious Disease Analysis and Jameel Institute, Imperial College London, London, UK.
  • Darzi A; Imperial College Healthcare NHS Trust, London, UK.
  • Cooke GS; Department of Infectious Disease, Imperial College London, London, UK.
  • Donnelly CA; School of Public Health, Imperial College London, London, UK.
  • Chadeau-Hyam M; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
Science ; 376(6600): eabq4411, 2022 06 24.
Article in English | MEDLINE | ID: covidwho-1861571
ABSTRACT
Rapid transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant has led to record-breaking incidence rates around the world. The Real-time Assessment of Community Transmission-1 (REACT-1) study has tracked SARS-CoV-2 infection in England using reverse transcription polymerase chain reaction (RT-PCR) results from self-administered throat and nose swabs from randomly selected participants aged 5 years and older approximately monthly from May 2020 to March 2022. Weighted prevalence in March 2022 was the highest recorded in REACT-1 at 6.37% (N = 109,181), with the Omicron BA.2 variant largely replacing the BA.1 variant. Prevalence was increasing overall, with the greatest increase in those aged 65 to 74 years and 75 years and older. This was associated with increased hospitalizations and deaths, but at much lower levels than in previous waves against a backdrop of high levels of vaccination.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Epidemics / SARS-CoV-2 / COVID-19 Type of study: Experimental Studies / Observational study / Randomized controlled trials Topics: Vaccines / Variants Limits: Aged / Humans Country/Region as subject: Europa Language: English Journal: Science Year: 2022 Document Type: Article Affiliation country: Science.abq4411

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Epidemics / SARS-CoV-2 / COVID-19 Type of study: Experimental Studies / Observational study / Randomized controlled trials Topics: Vaccines / Variants Limits: Aged / Humans Country/Region as subject: Europa Language: English Journal: Science Year: 2022 Document Type: Article Affiliation country: Science.abq4411