MOG-antibody-associated longitudinal extensive myelitis after ChAdOx1 nCoV-19 vaccination.
Mult Scler
; 28(7): 1159-1162, 2022 06.
Article
in English
| MEDLINE | ID: covidwho-1861992
ABSTRACT
This case report describes a 59-year-old man with myelin oligodendrocyte glycoprotein (MOG)-positive longitudinal extensive transverse myelitis (LETM) after being vaccinated with the COVID-19 vaccine ChAdOx1 nCoV-19. He presented with urinary retention, gait disturbance, hypoesthesia and brisk reflexes in his lower extremities without paresis. Due to the ineffectiveness of high-dose intravenous methylprednisolone, therapeutic plasma exchange was performed, gradually improving the patient's condition. Vaccination as a trigger for an excessive immunological response seems plausible, though unspecific for the ChAdOx1 nCoV-19 vaccine.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
/
ChAdOx1 nCoV-19
/
Myelitis, Transverse
Type of study:
Case report
/
Observational study
/
Prognostic study
Topics:
Vaccines
Limits:
Humans
/
Male
Language:
English
Journal:
Mult Scler
Journal subject:
Neurology
Year:
2022
Document Type:
Article
Affiliation country:
13524585211057512
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