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Transcriptomic perspectives of memory-like NK cells and aging.
Wang, Dandan; Malarkannan, Subramaniam.
  • Wang D; Blood Research Institute, Versiti Inc, 8727 Watertown Plank Rd, Milwaukee, WI, 53226, USA.
  • Malarkannan S; Department of Microbiology and Immunology, Medical College of Wisconsin (MCW), Milwaukee, WI, 53226, USA.
Genome Med ; 14(1): 57, 2022 05 25.
Article in English | MEDLINE | ID: covidwho-1862145
ABSTRACT
A recent study highlights the presence of a unique memory-like natural killer (NK) cell subset, which accumulates with aging and appears to associate withdisease severity in COVID-19 patients. While the clinical relevance of memory in NK cells is being debated, the molecular identity of this subset in the form of a single-cell transcriptome is essential to define their origin, longevity, functions, and disease relevance.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Aging / Killer Cells, Natural / Transcriptome / COVID-19 Type of study: Prognostic study Limits: Humans Language: English Journal: Genome Med Year: 2022 Document Type: Article Affiliation country: S13073-022-01059-1

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Aging / Killer Cells, Natural / Transcriptome / COVID-19 Type of study: Prognostic study Limits: Humans Language: English Journal: Genome Med Year: 2022 Document Type: Article Affiliation country: S13073-022-01059-1