Your browser doesn't support javascript.
Role of Microbiota in Viral Infections and Pathological Progression.
Mizutani, Taketoshi; Ishizaka, Aya; Koga, Michiko; Tsutsumi, Takeya; Yotsuyanagi, Hiroshi.
  • Mizutani T; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba 277-8562, Japan.
  • Ishizaka A; Division of Infectious Diseases, Advanced Clinical Research Center, the Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.
  • Koga M; Division of Infectious Diseases, Advanced Clinical Research Center, the Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.
  • Tsutsumi T; Division of Infectious Diseases, Advanced Clinical Research Center, the Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.
  • Yotsuyanagi H; Division of Infectious Diseases, Advanced Clinical Research Center, the Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.
Viruses ; 14(5)2022 05 01.
Article in English | MEDLINE | ID: covidwho-1862910
ABSTRACT
Viral infections are influenced by various microorganisms in the environment surrounding the target tissue, and the correlation between the type and balance of commensal microbiota is the key to establishment of the infection and pathogenicity. Some commensal microorganisms are known to resist or promote viral infection, while others are involved in pathogenicity. It is also becoming evident that the profile of the commensal microbiota under normal conditions influences the progression of viral diseases. Thus, to understand the pathogenesis underlying viral infections, it is important to elucidate the interactions among viruses, target tissues, and the surrounding environment, including the commensal microbiota, which should have different relationships with each virus. In this review, we outline the role of microorganisms in viral infections. Particularly, we focus on gaining an in-depth understanding of the correlations among viral infections, target tissues, and the surrounding environment, including the commensal microbiota and the gut virome, and discussing the impact of changes in the microbiota (dysbiosis) on the pathological progression of viral infections.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Viruses / Virus Diseases / Microbiota / Gastrointestinal Microbiome Limits: Humans Language: English Year: 2022 Document Type: Article Affiliation country: V14050950

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Viruses / Virus Diseases / Microbiota / Gastrointestinal Microbiome Limits: Humans Language: English Year: 2022 Document Type: Article Affiliation country: V14050950