OUTCOMES IN PATIENTS WITH COVID-19 COMPLICATED BY HIGH GRADE ATRIOVENTRICULAR BLOCK
Heart Rhythm
; 19(5):S53-S54, 2022.
Article
in English
| EMBASE | ID: covidwho-1867188
ABSTRACT
Background:
There is growing evidence showing that arrhythmias are one of the major complications of COVID-19.However, there are currently only a few case reports of high-grade atrioventricular block (AVB). We sought to describe a large case series of AVB as a complication of COVID-19.Objective:
The purpose of the current study is to describe a large case series of AVB as a complication of COVID-19.Methods:
We included a series of twenty-five (25)consecutive patients with confirmed COVID-19, who developed advanced AVB in a prospective observational multi-center study. Patients underwent clinical, laboratory evaluation, Holter, telemetry, Echocardiogram, Chest X-Ray, chest CT scan and cardiac MRIResults:
Of the 25 patients 13 were male with a mean age of 62+-13 years. 19 developed complete AVB, one a 31 AVB and five 21 AVB. None of the patients had a history of cardiac arrhythmia. AVB was not related to medication or intubation. Eighteen patients developed AVB during their hospitalization for COVID-19 and 7 after the first month as a late sequela. Five patients were asymptomatic, 6 presented syncope, seven dyspnea and seven dizziness. Eleven patients presented reverse AVB early by a high dose of corticosteroid in all of them, and combined with colchicine in 4 cases, with no recurrent episodes. 13 patients required a permanent pacemaker for persistent conduction defect (52%) and one died of ventricular fibrillation without pacemakerConclusion:
Advanced AVB could be a complication of COVID-19. The conduction disturbance was reversed by corticosteroids with or without colchicine in eleven of twenty five cases (44%)The resolution with corticosteroids of the advanced AVB in these patients could reflect the transient nature of the viral infection and the inflammatory response associated with it in some patients. 13 patients required a pacemaker(52%). Physicians should be aware of this complication.
colchicine; corticosteroid; adult; artificial heart pacemaker; atrioventricular block; cardiac rhythm management device; cardiovascular magnetic resonance; case study; clinical evaluation; clinical laboratory; complete heart block; complication; conference abstract; coronavirus disease 2019; dizziness; drug combination; drug megadose; dyspnea; echocardiography; faintness; female; heart arrhythmia; heart muscle conduction disturbance; heart ventricle fibrillation; hospitalization; human; inflammation; intubation; major clinical study; male; middle aged; outcome assessment; physician; prospective study; telemetry; thorax radiography; x-ray computed tomography
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Language:
English
Journal:
Heart Rhythm
Year:
2022
Document Type:
Article
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