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COVID-19 impact on routine immunisations for vaccine-preventable diseases: Projecting the effect of different routes to recovery.
Toor, Jaspreet; Li, Xiang; Jit, Mark; Trotter, Caroline L; Echeverria-Londono, Susy; Hartner, Anna-Maria; Roth, Jeremy; Portnoy, Allison; Abbas, Kaja; Ferguson, Neil M; Am Gaythorpe, Katy.
  • Toor J; MRC Centre for Global Infectious Disease Analysis, Jameel Institute, School of Public Health, Imperial College London, London, United Kingdom. Electronic address: j.toor@imperial.ac.uk.
  • Li X; MRC Centre for Global Infectious Disease Analysis, Jameel Institute, School of Public Health, Imperial College London, London, United Kingdom.
  • Jit M; London School of Hygiene and Tropical Medicine, London, United Kingdom; University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China.
  • Trotter CL; University of Cambridge, Cambridge, United Kingdom.
  • Echeverria-Londono S; MRC Centre for Global Infectious Disease Analysis, Jameel Institute, School of Public Health, Imperial College London, London, United Kingdom.
  • Hartner AM; MRC Centre for Global Infectious Disease Analysis, Jameel Institute, School of Public Health, Imperial College London, London, United Kingdom.
  • Roth J; MRC Centre for Global Infectious Disease Analysis, Jameel Institute, School of Public Health, Imperial College London, London, United Kingdom.
  • Portnoy A; Center for Health Decision Science, Harvard T H Chan School of Public Health, Boston, United States.
  • Abbas K; London School of Hygiene and Tropical Medicine, London, United Kingdom.
  • Ferguson NM; MRC Centre for Global Infectious Disease Analysis, Jameel Institute, School of Public Health, Imperial College London, London, United Kingdom.
  • Am Gaythorpe K; MRC Centre for Global Infectious Disease Analysis, Jameel Institute, School of Public Health, Imperial College London, London, United Kingdom. Electronic address: k.gaythorpe@imperial.ac.uk.
Vaccine ; 40(31): 4142-4149, 2022 07 29.
Article in English | MEDLINE | ID: covidwho-1867882
ABSTRACT
Over the past two decades, vaccination programmes for vaccine-preventable diseases (VPDs) have expanded across low- and middle-income countries (LMICs). However, the rise of COVID-19 resulted in global disruption to routine immunisation activities. Such disruptions could have a detrimental effect on public health, leading to more deaths from VPDs, particularly without mitigation efforts. Hence, as routine immunisation activities resume, it is important to estimate the effectiveness of different approaches for recovery. We apply an impact extrapolation method developed by the Vaccine Impact Modelling Consortium to estimate the impact of COVID-19-related disruptions with different recovery scenarios for ten VPDs across 112 LMICs. We focus on deaths averted due to routine immunisations occurring in the years 2020-2030 and investigate two recovery scenarios relative to a no-COVID-19 scenario. In the recovery scenarios, we assume a 10% COVID-19-related drop in routine immunisation coverage in the year 2020. We then linearly interpolate coverage to the year 2030 to investigate two routes to recovery, whereby the immunization agenda (IA2030) targets are reached by 2030 or fall short by 10%. We estimate that falling short of the IA2030 targets by 10% leads to 11.26% fewer fully vaccinated persons (FVPs) and 11.34% more deaths over the years 2020-2030 relative to the no-COVID-19 scenario, whereas, reaching the IA2030 targets reduces these proportions to 5% fewer FVPs and 5.22% more deaths. The impact of the disruption varies across the VPDs with diseases where coverage expands drastically in future years facing a smaller detrimental effect. Overall, our results show that drops in routine immunisation coverage could result in more deaths due to VPDs. As the impact of COVID-19-related disruptions is dependent on the vaccination coverage that is achieved over the coming years, the continued efforts of building up coverage and addressing gaps in immunity are vital in the road to recovery.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccine-Preventable Diseases / COVID-19 Type of study: Experimental Studies / Observational study Topics: Vaccines Limits: Humans Language: English Journal: Vaccine Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccine-Preventable Diseases / COVID-19 Type of study: Experimental Studies / Observational study Topics: Vaccines Limits: Humans Language: English Journal: Vaccine Year: 2022 Document Type: Article