Microbial Resistance to Antibiotics and Effective Antibiotherapy
Biomedicines
; 10(5):1121, 2022.
Article
in English
| ProQuest Central | ID: covidwho-1870521
ABSTRACT
Currently, the efficacy of antibiotics is severely affected by the emergence of the antimicrobial resistance phenomenon, leading to increased morbidity and mortality worldwide. Multidrug-resistant pathogens are found not only in hospital settings, but also in the community, and are considered one of the biggest public health concerns. The main mechanisms by which bacteria develop resistance to antibiotics include changes in the drug target, prevention of entering the cell, elimination through efflux pumps or inactivation of drugs. A better understanding and prediction of resistance patterns of a pathogen will lead to a better selection of active antibiotics for the treatment of multidrug-resistant infections.
Medical Sciences; antibiotic resistance; multidrug-resistant bacteria; mechanism of resistance; persistence; biofilms; antibiotherapy; Antimicrobial resistance; Public health; Morbidity; Penicillin; Coronaviruses; Multidrug resistance; Therapeutic targets; Pathogens; Drug resistance; Bacterial infections; Antibiotics; COVID-19
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Collection:
Databases of international organizations
Database:
ProQuest Central
Type of study:
Experimental Studies
Language:
English
Journal:
Biomedicines
Year:
2022
Document Type:
Article
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