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Treating Insulin Resistance with Intermittent Personalized Nutrition to Sustain Metabolic Health and Functioning Immune System for Risk Reduction of Viral Diseases Especially COVID-19 and Long-COVID.
Rohner, Markus; Schwarz, Peter E H; Bornstein, Stefan R.
  • Rohner M; EpiGeneticBalance AG, EpiGeneticBalance AG, CH-4310 Rheinfelden, Rheinfelden, Switzerland.
  • Schwarz PEH; Department of Medicine, Carl Gustav Carus, Prevention and Care of Diabetes, Technical University Dresden, Dresden, Germany.
  • Bornstein SR; Paul Langerhans Institute Dresden, German Center for Diabetes Research (DZD), Dresden, Germany.
Horm Metab Res ; 54(8): 567-570, 2022 Aug.
Article in English | MEDLINE | ID: covidwho-1873583
ABSTRACT
The Covid-19 pandemic has provided new and strong evidence for poor outcomes of viral infection in patients with poor metabolic health. Insulin resistance is at the root of many metabolic conditions and a key driver of their progression as it promotes ineffectual inflammation whilst impairing immune functions. In a vicious circle, insulin resistance facilitates SARS-CoV-2 infection, whilst infection drives insulin resistance. We discuss the underlying mechanisms and explore ways to improve metabolic health and prevent insulin resistance through early detection and targeted nutritional interventions. With proven efficacy in prediabetes, type 2 diabetes, and their cardiovascular and organ complications, as much as non-alcoholic liver disease, we argue to extend such approaches to ensure resilience to the current pandemic and viral challenges beyond.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Insulin Resistance / Diabetes Mellitus, Type 2 / COVID-19 Type of study: Diagnostic study / Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Horm Metab Res Year: 2022 Document Type: Article Affiliation country: A-1864-8234

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Insulin Resistance / Diabetes Mellitus, Type 2 / COVID-19 Type of study: Diagnostic study / Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Horm Metab Res Year: 2022 Document Type: Article Affiliation country: A-1864-8234