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Prevalence and Antifungal Susceptibility Profile of Oral Candida spp. Isolates from a Hospital in Slovakia.
Cernáková, Lucia; Lísková, Anna; Lengyelová, Libusa; Rodrigues, Célia F.
  • Cernáková L; Department of Microbiology and Virology, Faculty of Natural Sciences, Comenius University in Bratislava, 842 15 Bratislava, Slovakia.
  • Lísková A; Department of Clinical Microbiology, Nitra Faculty Hospital, 950 01 Nitra, Slovakia.
  • Lengyelová L; Department of Botany and Genetics, Faculty of Natural Sciences and Informatics, Constantine the Philosopher University in Nitra, 949 01 Nitra, Slovakia.
  • Rodrigues CF; TOXRUN-Toxicology Research Unit, Cooperativa de Ensino Superior Politécnico e Universitário-CESPU, 4585-116 Gandra, Portugal.
Medicina (Kaunas) ; 58(5)2022 Apr 22.
Article in English | MEDLINE | ID: covidwho-1875695
ABSTRACT
Oral fungal infections are a worldwide healthcare problem. Although Candida albicans is still the most common yeast involved in the infections of oral cavity, non-Candida albicans Candida species (NCACs) have been highly related to these infections, particularly in older, immunosuppressed or patients with long exposure to antimicrobial drugs. The goal of this work was to perform a quick epidemiological and mycological study on the oral samples collected from a laboratory of a hospital in Slovakia, for 60 days. The samples' identification was performed by Germ-tube formation test, CHROMID® Candida, Auxacolor 2, ID 32C automated method, and the antifungal susceptibility testing determined by E-test®. Results confirm that comparing with bacteria, yeasts still occur in the lower number, but there is a high rate of antifungal resistance (81.6%)-to, at least one drug-among the collected samples, particularly to azoles and 5'-FC, which is clinically noteworthy.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Candida / Antifungal Agents Type of study: Observational study / Prognostic study Limits: Aged / Humans Country/Region as subject: Europa Language: English Journal subject: Medicine Year: 2022 Document Type: Article Affiliation country: Medicina58050576

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Candida / Antifungal Agents Type of study: Observational study / Prognostic study Limits: Aged / Humans Country/Region as subject: Europa Language: English Journal subject: Medicine Year: 2022 Document Type: Article Affiliation country: Medicina58050576