Ki-67 expression level in placentas with COVID-19 infected women
Journal of Drug Delivery and Therapeutics
; 12(1-s):29-33, 2022.
Article
in English
| CAB Abstracts | ID: covidwho-1876380
ABSTRACT
Objective:
The SARS-CoV-2 virus, which emerged in December 2019 in Wuhan, China, spread very quickly in a short time and was declared a pandemic by the World Health Organization in March 2020. Physiological and immunological changes during pregnancy cause complications in respiratory tract infections. Complications by COVID-19 lead to a systemic effect that causes maternal and fetal mortality and morbidity. In this study, we aimed to investigate histopathological changes and Ki-67 expression in placentas of women with positive COVID-19 infection. StudyDesign:
Placentas of 10 samples COVID-19 positive and 10 samples Covid-19 negative pregnant patients who were hospitalized in the Gynecology and Obstetrics Clinic of Dicle University Faculty of Medicine were included in the study. Placental tissues were fixed in 10% formaldehyde (24 hours) and processed for routine paraffin wax tissue staining. Hematoxylin Eosin dye and Ki-67 immunohistochemical staining were performed.
Prion, Viral, Bacterial and Fungal Pathogens of Humans [VV210]; Human Reproduction and Development [VV060]; viral diseases; coronavirus disease 2019; human diseases; pandemics; pregnancy; women; public health; fetus; gynaecology; histology; histopathology; immunohistochemistry; morbidity; mortality; obstetrics; placenta; Severe acute respiratory syndrome coronavirus 2; man; Turkey; Severe acute respiratory syndrome-related coronavirus; Betacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; viruses; Homo; Hominidae; primates; mammals; vertebrates; Chordata; animals; eukaryotes; Mediterranean Region; OECD Countries; upper-middle income countries; very high Human Development Index countries; West Asia; Asia; Ki-67 antigen; viral infections; SARS-CoV-2; gestation; foetus; gynecology; death rate
Full text:
Available
Collection:
Databases of international organizations
Database:
CAB Abstracts
Language:
English
Journal:
Journal of Drug Delivery and Therapeutics
Year:
2022
Document Type:
Article
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