Your browser doesn't support javascript.
CORRELATION BETWEEN RS6265 SNP IN BDNF AND THE CONTEXT OF DIABETES TYPE II INVOLVEMENT IN IRAQI PATIENTS.
Abbas, Saly Naser; Obeid, Hajer Alaa; Alwan, Tahreer Shannan; Hassan, Saif M; Jawad, Mahmood J; Jawad, Mohammed J; Hadi, Najah R.
  • Abbas SN; AL-ZAHRAWI UNIVERSITY COLLEGE, KARBALA, IRAQ.
  • Obeid HA; AL-ZAHRAWI UNIVERSITY COLLEGE, KARBALA, IRAQ.
  • Alwan TS; AL-ZAHRAWI UNIVERSITY COLLEGE, KARBALA, IRAQ.
  • Hassan SM; AL-ZAHRAWI UNIVERSITY COLLEGE, KARBALA, IRAQ.
  • Jawad MJ; AL-ZAHRAWI UNIVERSITY COLLEGE, KARBALA, IRAQ.
  • Jawad MJ; UNIVERSITY OF KARBALA, KARBALA, IRAQ.
  • Hadi NR; UNIVERSITY OF KUFA, KUFA, IRAQ.
Wiad Lek ; 75(4 pt 1): 787-790, 2022.
Article in English | MEDLINE | ID: covidwho-1876551
ABSTRACT

OBJECTIVE:

The

aim:

In this study, we looked into the possible link between the G196A polymorphism in the BDNF gene and DM in Iraqi patients. PATIENTS AND

METHODS:

Materials and

methods:

By using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) approach, 100 subjects were genotyped for the G196A SNP of the BDNF gene, 50 as DM and 50 as controls, age-sex and ethnically matched healthy controls. Analysis of covariance (ANCOVA) was used to assess the association of this polymorphism, and genotype frequencies were compared between patients and healthy controls.

RESULTS:

Results:

Our result show that patient with the AG (Val-Met) genotype had a 40%of total DM patients than those and GG (Val-Val) genotypes. Therefore, we concluded that as a future aspect of the report the work can be further extended on proteomic level wherein the corresponding change occurred due to the mutation in the protein can be further detected at structural and functional level.

CONCLUSION:

Conclusions:

conclusion of our result was any patient with covid-19 must need to follow up for at least 1 month after recovery to notified of the post-Covid symptoms especially the male gender.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Brain-Derived Neurotrophic Factor / Diabetes Mellitus, Type 2 Type of study: Cohort study / Prognostic study Topics: Long Covid Limits: Humans / Male Country/Region as subject: Asia Language: English Journal: Wiad Lek Journal subject: Medicine Year: 2022 Document Type: Article Affiliation country: WLek202204107

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Brain-Derived Neurotrophic Factor / Diabetes Mellitus, Type 2 Type of study: Cohort study / Prognostic study Topics: Long Covid Limits: Humans / Male Country/Region as subject: Asia Language: English Journal: Wiad Lek Journal subject: Medicine Year: 2022 Document Type: Article Affiliation country: WLek202204107