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Different systemic rheumatic diseases as risk factors for COVID-19-related mortality.
Fragoulis, George E; Bournia, Vasiliki-Kalliopi; Sfikakis, Petros P.
  • Fragoulis GE; First Department of Propedeutic and Internal Medicine, Joint Academic Rheumatology Program, 75 Mikras Asias Str, 11527, Athens, Greece. geofragoul@yahoo.gr.
  • Bournia VK; First Department of Propedeutic and Internal Medicine, Joint Academic Rheumatology Program, 75 Mikras Asias Str, 11527, Athens, Greece.
  • Sfikakis PP; First Department of Propedeutic and Internal Medicine, Joint Academic Rheumatology Program, 75 Mikras Asias Str, 11527, Athens, Greece.
Clin Rheumatol ; 41(6): 1919-1923, 2022 Jun.
Article in English | MEDLINE | ID: covidwho-1877849
ABSTRACT
COVID-19 has been associated with increased morbidity and mortality, globally. Whether COVID-19-related mortality is increased in patients with systemic rheumatic diseases (SRDs) is still debatable. Although results are somewhat conflicting, there are a handful of nationwide studies published indicating that, in individuals with SRD, there is signal for increased adverse COVID-19-related outcomes and higher mortality. It appears that there are differences in COVID-19-related mortality across various SRDs. Besides, certain disease-specific (disease activity, disease duration, medication received) and/or other features (e.g. comorbidities) seem to also affect COVID-19-related mortality in SRD patients. Herein, we wanted to highlight that a more individualized approach taking into consideration the effect of the aforementioned factors into the risk calculation for COVID-19 adverse outcomes, including mortality, in SRD patients is warranted. A multinational study based on nationwide data, examining all common SRDs and stratifying accordingly, would be of interest, toward this direction. Key Points • It is still debatable whether Covid-19-related mortality is increased in patients with sytemic rheumatic diseases (SRD). • Disease-specific risk factors (e.g. type of SRD, disease activity) should be taken into account in risk assessment for Covid-19-releted outcomes in SRD patients.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Rheumatic Diseases / COVID-19 Type of study: Observational study / Prognostic study Limits: Humans Language: English Journal: Clin Rheumatol Year: 2022 Document Type: Article Affiliation country: S10067-022-06190-3

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Rheumatic Diseases / COVID-19 Type of study: Observational study / Prognostic study Limits: Humans Language: English Journal: Clin Rheumatol Year: 2022 Document Type: Article Affiliation country: S10067-022-06190-3