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Patient-reported outcomes of prepectoral implant-based breast reconstruction: Early results from the pre-bra prospective multi-centre cohort study
European Journal of Surgical Oncology ; 48(5):e189-e190, 2022.
Article in English | EMBASE | ID: covidwho-1881968
ABSTRACT

Introduction:

Prepectoral breast reconstruction (PPBR) has been widely adopted due to a perceived reduction in post-operative pain and improved patient satisfaction but high-quality evidence to support these benefits is lacking. The Pre-BRA prospective multicentre cohort study aimed to explore the safety and effectiveness of PPBR prior to definitive evaluation in an RCT. Here we report the 1st analysis of the 18-month patient-reported outcome (PRO) data.

Methods:

Consecutive women undergoing PPBR at 40 UK centres were recruited to the Pre-BRA study between July 2019 and Dec 2020 with a 4 month pause to recruitment (March-July 2020) due to the COVID-19 pandemic. Demographic, operative, oncological, and 3-month safety data were collected. Women were asked to complete the BREAST-Q© (V2.0) at baseline, 3 and 18-months. Questionnaires were scored according to the developers' instructions and compared with the 18-month PRO results from the iBRA study which included mainly subpectoral mesh-assisted reconstruction.

Results:

347 women underwent PPBR in the Pre-BRA study. Of these, 221 patients recruited pre-COVID have reached 18-month follow-up and 164 (74%) have completed the 18-month questionnaire. The median Satisfaction with Breasts score was 60 (48.5-71;0-100) [inter-quartile range;range] compared to 59 (48-71;0-100) in the UK iBRA study.

Conclusions:

Satisfaction with breasts at 18-months following surgery appears to be equivalent following pre and subpectoral breast reconstruction. Further analysis is needed, but this study supports the need for an RCT to definitively compare techniques and establish best practice for implant-based reconstruction.
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Full text: Available Collection: Databases of international organizations Database: EMBASE Type of study: Cohort study / Observational study / Prognostic study Language: English Journal: European Journal of Surgical Oncology Year: 2022 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: EMBASE Type of study: Cohort study / Observational study / Prognostic study Language: English Journal: European Journal of Surgical Oncology Year: 2022 Document Type: Article