Mammary analogue secretory carcinoma presenting with cervical lymphadenopathy: A rare case report with review of the literature.
Int J Surg Case Rep
; 95: 107132, 2022 Jun.
Article
in English
| MEDLINE | ID: covidwho-1882096
ABSTRACT
INTRODUCTION:
Mammary analogue secretory carcinoma is a rare malignant tumor of the salivary glands that typically involves the major glands. The aim of the current study is to report a rare case of mammary analogue secretory carcinoma that presented with left cervical lymphadenopathy. CASE REPORT A 59-year-old lady presented with left cervical lymphadenopathy. Tissue biopsy and immunohistochemistry revealed metastatic carcinoma, favoring ovarian origin. Staging workup was performed and, ultimately, the patient was treated as having a carcinoma of unknown primary. After showing partial response to therapy, left side neck dissection was performed. Based on better assessment of the histologic picture and a broader panel of immunohistochemistry performed on the excision specimen, the final diagnosis was that of mammary analogue secretory carcinoma.DISCUSSION:
Mammary analogue secretory carcinoma is usually an indolent salivary gland carcinoma, with the majority of patients presenting with a slow-growing, painless mass measuring approximately 2 cm in size, and a reported duration ranging from 2 months to several years. In certain cases, pain and facial paralysis have been reported. It could also be found incidentally during radiologic assessment for thyroid illness or routine dental screening.CONCLUSION:
Diagnosing mammary analogue secretory carcinoma is challenging, and this should be in the differential diagnosis list of metastatic carcinomas to cervical lymph nodes.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Case report
/
Diagnostic study
Language:
English
Journal:
Int J Surg Case Rep
Year:
2022
Document Type:
Article
Affiliation country:
J.ijscr.2022.107132
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