[Comorbidities and demographic factors associated with severe COVID-19 outcomes in a Chilean hospital]. / Factores demográficos y comorbilidades asociadas a severidad de COVID-19 en un hospital chileno: el rol clave del nivel socioeconómico.
Rev Med Chil
; 149(8): 1141-1149, 2021 Aug.
Article
in Spanish
| MEDLINE | ID: covidwho-1884531
ABSTRACT
BACKGROUND:
Several risk factors are associated with COVID-19 severity and death, such as advanced age, male sex, and the presence of comorbidities.AIM:
To study the effect of these risk factors and socioeconomic variables on the outcome of Chilean patients admitted with COVID-19 to a Chilean public hospital. MATERIAL ANDMETHODS:
Review of medical records of patients admitted to a Chilean public hospital with a positive PCR test for COVID-19, Chile from March to June 2020. The outcome variable was severity (ICU admission or death). The exposure variables were age, sex, socioeconomic level, and comorbidities. A multivariable logistic regression analysis was performed.RESULTS:
Of 1,141 confirmed cases, 266 cases had a severe evolution (23.3%), including 147 deaths (fatality 12.9%). Advanced age and low socioeconomic status were the variables most strongly associated with severity. An age of 80 years or over had an odds ratio (OR) = 11.1 [95% confidence intervals (CI) 5.22-23.53]. The OR [95% CI] for a low socioeconomic level was 3.1 [1.1-8.5]. The figure for male sex was 2.13 [1.5-3.0], for chronic kidney disease was 2.65 [1.49-4.73], for obesity was 2.36 [1.65-3.39], and for diabetes 1.78 [1.22-2.61]. No significant association with severity was found for high blood pressure, chronic pulmonary disease, cardiovascular disease, or smoking.CONCLUSIONS:
Following age, a low socioeconomic level was the factor with the higher association with a poor outcome or severe evolution of COVID-19.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
/
Male
Country/Region as subject:
South America
/
Chile
Language:
Spanish
Journal:
Rev Med Chil
Year:
2021
Document Type:
Article
Affiliation country:
S0034-98872021000801141
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