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Seroprevalence of Antibodies Against SARS-CoV-2 Among Health Care Workers at a Tertiary Care Hospital in Uttarakhand: A Retrospective Study.
Saini, Amit K; Panda, Prasan K; Bahurupi, Yogesh; Omar, Balram; T, Akhil; Panwar, Pooja; Sharma, Maneesh.
  • Saini AK; Department of Nursing, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
  • Panda PK; Department of Internal Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
  • Bahurupi Y; Department of Community & Family Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
  • Omar B; Department of Microbiology, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
  • T A; Department of Nursing, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
  • Panwar P; Department of Nursing, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
  • Sharma M; Department of Nursing, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Cureus ; 14(5): e24840, 2022 May.
Article in English | MEDLINE | ID: covidwho-1884686
ABSTRACT
Background The number of confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections is vastly underestimated. In this context, seroprevalence surveys are of utmost importance to assess the proportion of the population that has already developed antibodies against the virus and might potentially be protected against subsequent infection. Health care workers (HCWs) face a greater risk of developing SARS-CoV-2. Therefore, the present retrospective study was undertaken to estimate the prevalence of antibodies against SARS-CoV-2 among healthcare workers at a tertiary care institute in Uttarakhand, India. Material and methods Data were gathered from hospital records of 704 healthcare workers admitted to the coronavirus disease 2019 (COVID-19) unit and attended the COVID OPD of the tertiary care institute between July 15 to Aug 14, 2020. Result Out of the 704 recruited participants, 14 (1.99%) were seropositive for immunoglobulin G (IgG) antibodies against SARS-CoV-2. The cumulative prevalence of SARS-CoV-2 infection (presence of antibodies or past or current positive reverse transcription-polymerase chain reaction (RT-PCR)) was 4.40%. Conclusion The present study shows a low prevalence of SARS-CoV-2 IgG antibodies among health care workers. In addition, posting in COVID-19-positive areas was not associated with increased seropositivity. More studies are warranted to assess IgG/IgM antibodies against SARS-CoV-2 among those HCWs who are exposed to COVID-19 patients.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study Language: English Journal: Cureus Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study Language: English Journal: Cureus Year: 2022 Document Type: Article