Anti-SARS-CoV-2 IgG antibodies pre-and post-vaccination behavior in health workers from a Guatemalan cancer center
administrative personnel |adult |ageusia |anosmia |article |cancer center |chest tightness |controlled study |coronavirus disease 2019 |diagnosis |female |health care personnel |human |major clinical study |male |nurse |prevalence |vaccination |endogenous compound |immunoglobulin G |immunoglobulin G antibody |SARS-CoV-2 antibody |vaccine
; 2022(Gaceta Medica de Mexico)
Article
in Spanish
| WHO COVID | ID: covidwho-1884916
ABSTRACT
Introduction:
The study of anti-SARS-CoV-2 IgG antibodies allows asymptomatic individuals with COVID-19 to be identified, and post-infection and post-vaccination immunity status to be evaluated.Objective:
To know the behavior of anti-SARS-CoV-2 IgG antibodies before and after vaccination in workers of a cancer center.Methods:
Prior to the application of the vaccine, the presence of anti-SARS-CoV-2 IgG antibodies (n = 171) was analyzed by evaluating anti-N IgG antibodies;post-vaccination, after receiving the second dose, anti-S IgG antibodies were evaluated (n = 60).Results:
Prior to vaccination, IgG antibodies were present in 18.71% of participants;they were detected in 65.22% of those with prior history of COVID-19 diagnosis and in 11.49% of those without it. The positions with the highest prevalence were nurses (28.26%), paramedics (27.59%) and administrative workers (27.78%), p < 0.01. Anosmia, ageusia and chest tightness were associated with the presence of IgG (p < 0.05). Post-vaccination, all participants developed IgG antibodies;people with a previous COVID-19 diagnosis had higher titers 10,277 vs. 6,819 AU/mL, p < 0.001.Conclusions:
The study of anti-SARS-CoV-2 IgG allowed asymptomatic health workers to be identified. A high percentage of participants with prior COVID-19 diagnosis had antibodies. All participants developed IgG after vaccination, with higher titers being identified in those with previous infection.
Full text:
Available
Collection:
Databases of international organizations
Database:
WHO COVID
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
Topics:
Vaccines
Country/Region as subject:
Central America
/
Guatemala
Language:
Spanish
Journal:
Administrative personnel |adult |ageusia |anosmia |article |cancer center |chest tightness |controlled study |coronavirus disease 2019 |diagnosis |female |health care personnel |human |major clinical study |male |nurse |prevalence |vaccination |endogenous compound |immunoglobulin G |immunoglobulin G antibody |SARS-CoV-2 antibody |vaccine
Document Type:
Article
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