Role of Dexmedetomidine in Perioperative Management of Pheochromocytoma
Journal of Cardiovascular Disease Research
; 13(1):884-893, 2022.
Article
in English
| EMBASE | ID: covidwho-1887445
ABSTRACT
The prevalence of Pheochromocytoma in pat ient with hypertension is 0.1 -0.6%. These types of tumours are known for unpredictable perioperative course and hemodynamic instability. Various different drugs and anaesthesia techniques can be used to tackle these situations. Dexmedetomidine is emerged as newer agent with better hemodynamic stability, reducing requirement of other anaesthesia drugs, blunting of sympathoadrenal response in resection of Pheochromocytoma. We report four cases operated between January 2021 to June 2021.Preoperative preparation was done with α and β blockade. Dexmedetomidine was used during induction as 1 mcg/kg over 10 mins followed by 0.7mcg/kg/hr intraoperatively. Combination of Dexmedetomidine, Fentanyl, NTG, Isoflurane and Epidural analgesia was used. IF needed boluses of Esmolol and Labetalol were used during tumor manipulation. All the patients had an uneventful perioperative course. Dexmedetomidine with pre-operative α and β blockade reduce the need of other drugs intraoperatively and can be used as anaesthetic adjunct to maintain steady hemodynamic.
arterial line; central venous catheter; epidural catheter; adrenalin plus lidocaine; amiodarone; amlodipine; bupivacaine; dexmedetomidine; dopamine; epinephrine; esmolol; fentanyl; glyceryl trinitrate; hydrochlorothiazide plus telmisartan; isoflurane; labetalol; lidocaine; metadrenalin; metoprolol; midazolam; noradrenalin; normetadrenalin; prazosin; propofol; propranolol; Ringer lactate solution; telmisartan; vanilmandelic acid; vecuronium; adrenalectomy; adrenalin urine level; adult; alpha adrenergic receptor blocking; anesthesia induction; antihypertensive therapy; arterial pressure; article; beta adrenergic receptor blocking; case report; clinical article; combination drug therapy; coronavirus disease 2019; dopamine urine level; epidural analgesia; female; fluid resuscitation; headache; heart palpitation; heart right bundle branch block; heart ventricle tachycardia; high resolution computer tomography; human; hypertension; intermittent positive pressure ventilation; male; noradrenalin urine level; nuclear magnetic resonance imaging; open surgery; perioperative medicine; pheochromocytoma; preoperative evaluation; sweating; tumor volume; young adult
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Database:
EMBASE
Language:
English
Journal:
Journal of Cardiovascular Disease Research
Year:
2022
Document Type:
Article
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