Vasculitis flare after COVID-19: report of two cases in patients with preexistent controlled IgA vasculitis and review of the literature.
Rheumatol Int
; 42(9): 1643-1652, 2022 09.
Article
in English
| MEDLINE | ID: covidwho-1888853
ABSTRACT
COVID-19 has been related to several autoimmune diseases, triggering the appearance of autoantibodies and endothelial dysfunction. Current evidence has drawn attention to vasculitis-like phenomena and leukocytoclastic vasculitis in some COVID-19 patients. Moreover, it has been hypothesized that COVID-19 could induce flares of preexisting autoimmune disorders. Here, we present two patients with previously controlled IgA vasculitis who developed a renal and cutaneous flare of vasculitis after mild COVID-19, one of them with new-onset ANCA vasculitis. These patients were treated with glucocorticoids and immunosuppressants achieving successful response. We also provide a focused literature review and conclude that COVID-19 may be associated with triggering of vasculitis and could induce flares of previous autoimmune diseases.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
IgA Vasculitis
/
Autoimmune Diseases
/
Vasculitis
/
Vasculitis, Leukocytoclastic, Cutaneous
/
COVID-19
Type of study:
Case report
/
Diagnostic study
/
Experimental Studies
/
Reviews
Topics:
Long Covid
Limits:
Humans
Language:
English
Journal:
Rheumatol Int
Year:
2022
Document Type:
Article
Affiliation country:
S00296-022-05153-w
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