Factors associated with vaccination against Covid-19 in pregnant and hospitalized postpartum women: A retrospective cohort study.
PLoS One
; 17(6): e0269091, 2022.
Article
in English
| MEDLINE | ID: covidwho-1892321
ABSTRACT
OBJECTIVE:
To analyze the characteristics associated with vaccination against Covid-19 in pregnant and postpartum women with Severe Acute Respiratory Syndrome in Brazil and to investigate a possible association between vaccination and the clinical course and outcome of the disease.METHODS:
Retrospective cohort study of hospitalized pregnant and postpartum women diagnosed with Severe Acute Respiratory Syndrome (SARS) by SARS-CoV-2, presenting onset of signs and symptoms between May and October 2021. Secondary data were used, available in the Influenza Epidemiological Surveillance Information System (SIVEP-Gripe). Data were analyzed using the SPSS statistical program, medians were applied to present continuous variables and frequencies, and proportions were calculated for categorical variables, using logistic and multivariate regression analysis.RESULTS:
The final study population included 3,585 pregnant and postpartum women, of whom 596 (16.6) were vaccinated 443 (74.3%) received one dose and 153 (25.7%) received two doses. They were factors associated with non-vaccination against Covid-19 age ≤ 19 anos (OR 2.57; IC95% 1.40;4.71), non-white women (OR 1.34; IC95% 1.07;1.67) and those who required ventilatory support (OR 1.51; IC95% 1.19;1.90) and invasive ventilation (OR 2.05; IC95% 1.37;3.08). On the other hand, vaccination was associated with advanced maternal age (OR 0.60; IC95% 0.48;0.76), presence of comorbidities (OR 0.57; IC95% 0.45;0.72) and loss of taste (OR 0.63; IC95% 0.48;0.82).CONCLUSIONS:
Demographic, ethnic-racial and clinical characteristics were associated with the vaccination status of pregnant and postpartum women with SARS by SARS-CoV-2 in Brazil. Vaccination against Covid-19 in the obstetric population has already shown positive results in the evolution of severe cases, which reiterates its importance. It is essential that health services advance vaccination against Covid-19 in the obstetric population, especially adolescentes and non-white women.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pregnancy Complications, Infectious
/
COVID-19
Type of study:
Cohort study
/
Diagnostic study
/
Observational study
/
Prognostic study
Topics:
Vaccines
Limits:
Female
/
Humans
/
Pregnancy
Language:
English
Journal:
PLoS One
Journal subject:
Science
/
Medicine
Year:
2022
Document Type:
Article
Affiliation country:
Journal.pone.0269091
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