Application of Silver Nanoparticles as a New Alternative Antiviral Agent for SARS-CoV-2: A Review
Current Nanoscience
; 18(4):465-477, 2022.
Article
in English
| ProQuest Central | ID: covidwho-1892481
ABSTRACT
Background:
Today, SARS-CoV-2 (COVID-19), a viral disease caused by the novel coronavirus (a tiny crowned virus), has become one of the threats for human beings all over the world and caused the death of millions of people worldwide. Many vaccines have been developed and administered to people in several countries;however, due to their propensity to create new strains, it appears that curing all corona strains will be challenging. So, it is necessary to identify the structure of the virus, mechanism of action, and its antiviral activities against drugs and other functional materials.Methods:
AgNPs have unique physicochemical and antimicrobial properties. This review describes the structure and nature of the virus and the mechanism of action of an antiviral drug such as silver nanoparticles (AgNPs) with the virus. In addition, different methods for synthesis of AgNPs, application of AgNPs as an antiviral agent against influenza virus, human immuno deficiency virus (HIV), herpes simplex virus type 1 (HSV-1), hepatitis B virus (HBV), polio virus, respiratory syncytial virus (RSV), are discussed. Also, the most probable applications and properties of AgNPs that can help prepare it as an antiviral agent are discussed.Results:
The use of AgNPs against various viruses, including the coronavirus family, is found to be effective;therefore, it can be considered for the development of antiviral agents, disinfectants, antiviral coated mask, and their therapeutic use against the treatment of novel coronavirus with minimum side effect and great efficiency.Conclusion:
AgNPs were successfully used for the treatment of various viral diseases of the coronavirus family such as H1N1, H3N2, influenza, even for SARS and MERS coronaviruses. AgNPs coated masks, disinfectants, fabrics, wipes, and inhalation systems are effective for the inhibition of SARS-CoV-2 infection. Since sanitizers have a temporary effect, the development of some other potential alternatives having low toxicity, ease of use, long lasting efficiency, health cautiousness, minimum side effect, sustainable fabrics is required.
Medical Sciences; AgNPs; H1N1; H3N2; SARS-CoV-2; antiviral agent; green synthesis; Hepatitis B; Toxicity; Inhalation; Nanoparticles; Severe acute respiratory syndrome coronavirus 2; Herpes simplex; Viral diseases; COVID-19; Silver; Antiviral agents; Antiinfectives and antibacterials; Respiration; Antiviral activity; Disinfectants; Influenza; Side effects; Viruses; Public health; Functional materials; Coronaviruses; Strains (organisms); Sanitizers; Fabrics; Vaccines; Coated masks; Antiseptics; Health services; Severe acute respiratory syndrome; Human immunodeficiency virus--HIV; System effectiveness
Full text:
Available
Collection:
Databases of international organizations
Database:
ProQuest Central
Language:
English
Journal:
Current Nanoscience
Year:
2022
Document Type:
Article
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