SARS-COV-2 a trigger of myelin oligodendrocyte glycoprotein-associated disorder.
Ann Clin Transl Neurol
; 9(8): 1296-1301, 2022 08.
Article
in English
| MEDLINE | ID: covidwho-1894573
ABSTRACT
SARS-COV-2 frequently cause neurological disorders and is sometimes associated with onset of autoimmune diseases affecting the nervous system. Over recent years, a rare but distinct diagnosis designated myelin oligodendrocyte glycoprotein-associated disorder (MOGAD) has been recognized in patients with attacks of optic neuritis, myelitis, or encephalomyelitis and increased levels of anti-MOG antibodies. The cause of MOGAD is unknown. However, there have been reports of single cases of MOGAD in patients with Covid-19 infection. We report a series of SARS-CoV-2 positive patients that developed MOGAD, but a homology search did not support a cross-reactive immune response to SARS-CoV-2 spike-protein and MOG.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Optic Neuritis
/
COVID-19
Type of study:
Randomized controlled trials
Limits:
Humans
Language:
English
Journal:
Ann Clin Transl Neurol
Year:
2022
Document Type:
Article
Affiliation country:
Acn3.51609
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