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Prioritizing Pregnant Women for Coronavirus Disease 2019 Vaccination in African Countries.
Nachega, Jean B; Sam-Agudu, Nadia A; Siedner, Mark J; Rosenthal, Philip J; Mellors, John W; Zumla, Alimuddin; Hermans, Michel P; Ntakwinja, Mukanire B; Mukwege, Denis M; Langenegger, Eduard; Mofenson, Lynne M.
  • Nachega JB; Department of Epidemiology, Infectious Diseases and Microbiology, and Center for Global Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Sam-Agudu NA; Departments of Epidemiology and International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
  • Siedner MJ; Department of Medicine, Division of Infectious Diseases, Stellenbosch University Faculty of Medicine and Health Sciences, Cape Town, South Africa.
  • Rosenthal PJ; International Research Center of Excellence, Institute of Human Virology Nigeria, Abuja, Nigeria.
  • Mellors JW; Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
  • Zumla A; Department of Paediatrics and Child Health, University of Cape Coast School of Medical Sciences, Cape Coast, Ghana.
  • Hermans MP; Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Ntakwinja MB; Mbarara University of Science and Technology, Mbarara, Uganda.
  • Mukwege DM; Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, San Francisco, California, USA.
  • Langenegger E; Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
  • Mofenson LM; Center for Clinical Microbiology, Division of Infection and Immunity, University College London, London, United Kingdom.
Clin Infect Dis ; 75(8): 1462-1466, 2022 Oct 12.
Article in English | MEDLINE | ID: covidwho-1895806
ABSTRACT
Coronavirus disease 2019 (COVID-19) in pregnancy is associated with excess maternal and infant morbidity and mortality in both African and higher-resource settings. Furthermore, mounting evidence demonstrates the safety and efficacy of COVID-19 vaccination for pregnant women and infants. However, national guidelines in many African countries are equivocal or lack recommendations on COVID-19 vaccine in pregnancy. We summarize key data on COVID-19 epidemiology and vaccination among pregnant African women to highlight major barriers to vaccination and recommend 4 interventions. First, policymakers should prioritize pregnant women for COVID-19 vaccination, with a target of 100% coverage. Second, empirically supported public health campaigns should be sustainably implemented to inform and support pregnant women and their healthcare providers in overcoming vaccine hesitancy. Third, COVID-19 vaccination for pregnant women should be expanded to include antenatal care, obstetrics/gynecology, and targeted mass vaccination campaigns. Fourth, national monitoring and evaluation of COVID-19 vaccine uptake, safety, surveillance, and prospective outcomes assessment should be conducted.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study Topics: Vaccines Limits: Female / Humans / Infant / Pregnancy Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2022 Document Type: Article Affiliation country: Cid

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study Topics: Vaccines Limits: Female / Humans / Infant / Pregnancy Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2022 Document Type: Article Affiliation country: Cid