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Use of disease-modifying drugs during pregnancy and breastfeeding.
Dobson, Ruth; Hellwig, Kerstin.
  • Dobson R; Preventive Neurology Unit, Queen Mary University of London.
  • Hellwig K; Department of Neurology, Royal London Hospital, Barts Health NHS Trust, London, UK.
Curr Opin Neurol ; 34(3): 303-311, 2021 06 01.
Article in English | MEDLINE | ID: covidwho-1895868
ABSTRACT
PURPOSE OF REVIEW The fact that multiple sclerosis (MS) predominantly affects women has been recognized for many years. As the age at diagnosis is decreasing, and treatment options are becoming more complex, increasing numbers of women are facing decisions about the use of disease modifying therapy (DMT) in and around pregnancy. RECENT

FINDINGS:

New data are rapidly becoming available, particularly regarding the safety of therapies in both pregnancy and breastfeeding. Effective treatment and suppression of relapses is key to ensuring good outcomes in the longer term for the woman, however this must be balanced against individual risk of relapse and risks to the fetus. Women should be advised that it is possible to breastfeed while taking selected DMT.

SUMMARY:

In this review, we discuss evidence surrounding the safety of DMTs in both pregnancy and breastfeeding, and use this knowledge to suggest approaches to pregnancy and family planning in women with MS.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Breast Feeding Type of study: Prognostic study Limits: Female / Humans / Pregnancy Language: English Journal: Curr Opin Neurol Journal subject: Neurology Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Breast Feeding Type of study: Prognostic study Limits: Female / Humans / Pregnancy Language: English Journal: Curr Opin Neurol Journal subject: Neurology Year: 2021 Document Type: Article