CT severity score: an imaging biomarker to estimate the severity of COVID-19 pneumonia in vaccinated and non-vaccinated population
Egyptian Journal of Radiology and Nuclear Medicine
; 53(1), 2022.
Article
in English
| EMBASE | ID: covidwho-1896398
ABSTRACT
Background:
In India, two vaccines received emergent use authorization, namely Covishield (a brand of the Oxford—Astra Zeneca vaccine manufactured by the Serum institute of India) and Covaxin (developed by Bharat Biotech) against COVID-19 disease. Chest CT is an objective way to assess the extent of pulmonary parenchymal involvement. This study aims to estimate the disease severity and outcome due to COVID-19 among vaccinated and non-vaccinated symptomatic patients and compare the same in Covishield versus Covaxin recipients using CT severity score.Results:
A total of 306 patients were retrospectively evaluated. The mean age was 62.56 ± 8.9 years, and males [n-208 (67.97%)] were commonly affected. Of 306 patients, 143 were non-vaccinated (47%), 124 were partially vaccinated (40%), and 39 were completely vaccinated (13%). CT severity scores were reduced in both Covishield and Covaxin recipients in comparison with the non-vaccinated group [χ2 (2) = 16.32, p < 0.001]. There is a reduction in LOS among the vaccinated group, predominantly among the Covishield recipients.Conclusion:
Vaccination confers protection from severe SARS-CoV2 infection and is associated with an overall reduction in mortality.
breathing frequency monitor; computed tomography scanner; picture archiving and communication system; covaxin; SARS-CoV-2 vaccine; vaxzevria; adult; aged; article; clinical outcome; cohort analysis; comparative effectiveness; controlled study; coronavirus disease 2019; disease severity; disease severity assessment; drug efficacy; female; ground glass opacity; high resolution computer tomography; human; length of stay; major clinical study; male; middle aged; multidetector computed tomography; observational study; recipient; retrospective study; single drug dose; thorax radiography; vaccination; vaccinee; very elderly; covishield; Ingenuity core
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Prognostic study
Topics:
Vaccines
Language:
English
Journal:
Egyptian Journal of Radiology and Nuclear Medicine
Year:
2022
Document Type:
Article
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