The study of andrographolide contents in different parts of Andrographis paniculata (Burm. f.) Nees at different harvesting periods from Muak Lek, Saraburi
Journal of Traditional Thai and Alternative Medicine
; 20(1):141-149, 2022.
Article
in Thaï
| CAB Abstracts | ID: covidwho-1897660
ABSTRACT
Andrographis paniculata (Burm. f.) Nees (fa thalai chon in Thai) is a medicinal plant that naturally grows in Muak Lek district, Saraburi province. During the flowering stage (mature plant), its andrographolide contents in various parts, from high to low, namely leaves, aerial parts, stems and flowers are 5.11%, 4.90%, 0.68% and 1.90% w/w respectively;and in the pre-flowering stage (young plant) the contents are 3.65%, 2.95% and 1.03% w/w respectively. For the treatment of COVID-19 with Andrographis herbal drug, at the andrographolide dose of 180 mg daily for 5 days, 19.6 g of fresh leaves from the young plant or 14.0 g of fresh leaves from the mature plant should be taken. As for the decoction of aerial parts of the mature plant, 2.5 240-mL glasses should be taken per day. But tea from fresh leaves, which is drunk without the pulp, has a too low andrographolide content to achieve the conventional dose for COVID-19 treatment. The results of this study are useful for the public who want to use their own fresh Andrographis herb to treat COVID-19 by themselves. The proper amount has to be calculated based on the andrographolide content in the formula they use.
Horticultural Crops [FF003]; Non-food/Non-feed Plant Products [SS200]; Composition and Quality of Non-food/Non-feed Plant Products [SS230]; Animal and in vitro Models for Pharmaceuticals [VV450]; Prion, Viral, Bacterial and Fungal Pathogens of Humans [VV210]; Pesticides and Drugs; Control [HH405]; medicinal plants; leaves; plant composition; plant extracts; chemical composition; stems; flowers; coronavirus disease 2019; human diseases; antiviral properties; viral diseases; Andrographis paniculata; Severe acute respiratory syndrome coronavirus 2; man; plants; Thailand; Andrographis; Acanthaceae; Lamiales; eudicots; angiosperms; Spermatophyta; eukaryotes; APEC countries; ASEAN Countries; high Human Development Index countries; South East Asia; Asia; upper-middle income countries; Severe acute respiratory syndrome-related coronavirus; Betacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; viruses; Homo; Hominidae; primates; mammals; vertebrates; Chordata; animals; drug plants; medicinal herbs; officinal plants; chemical constituents of plants; SARS-CoV-2; anti-viral properties; viral infections
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Collection:
Databases of international organizations
Database:
CAB Abstracts
Language:
Thaï
Journal:
Journal of Traditional Thai and Alternative Medicine
Year:
2022
Document Type:
Article
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