Chronic demyelinating polyradiculoneuropathy presented after SARS CoV2 mild infection- a case report

ABSTRACT

COVID19 is an infectious disease caused by the SARS CoV-2 virus that emerged in Wuhan, China, in 2019. Common complaints are dry cough, dyspnea, fever, myalgia, headache, anosmia, and ageusia. This influenza-like virus has a nootropic potential, as seen in patients complaining of various neurological symptoms in the course of the disease or shortly after resolution. Autoimmune diseases in the nervous system can occur as a complication of viral infection. Mechanisms including molecular mimicry, bystander activation, epitope spreading can activate viral-linked autoimmunity. Therefore, we present a case of classical chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) with onset one month after being diagnosed with a mild form of COVID19 in a patient with a history of diabetes and obesity. The case has been followed up for a year, being investigated thoroughly, including nerve conduction studies, spinal tap, and blood tests. The patient received periodical courses of intravenous immunoglobulin therapy.