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Clinical characteristics and outcomes of confirmed COVID-19 patients in the early months of the pandemic in Tanzania: a multicenter cohort study.
Mnyambwa, Nicholaus P; Lubinza, Clara; Ngadaya, Esther; Senkoro, Mbazi; Kimaro, Godfather; Kagaruki, Gibson B; Binagi, Stanley; Malima, Amani; Kazyoba, Paul; Oriyo, Ndekya; Mghamba, Janneth M; Fredrick, Aman; Ramaiya, Kaushik; Zumla, Alimuddin; Jaffar, Shabbar; Mfinanga, Sayoki G.
  • Mnyambwa NP; National Institute for Medical Research, Muhimbili Research Centre, Dar es Salaam, Tanzania.
  • Lubinza C; Alliance for Africa Health and Research (A4A), Dar es Salaam, Tanzania.
  • Ngadaya E; National Institute for Medical Research, Muhimbili Research Centre, Dar es Salaam, Tanzania.
  • Senkoro M; National Institute for Medical Research, Muhimbili Research Centre, Dar es Salaam, Tanzania.
  • Kimaro G; Alliance for Africa Health and Research (A4A), Dar es Salaam, Tanzania.
  • Kagaruki GB; National Institute for Medical Research, Muhimbili Research Centre, Dar es Salaam, Tanzania.
  • Binagi S; National Institute for Medical Research, Muhimbili Research Centre, Dar es Salaam, Tanzania.
  • Malima A; National Institute for Medical Research, Muhimbili Research Centre, Dar es Salaam, Tanzania.
  • Kazyoba P; Amana Regional Referral Hospital, Dar es Salaam, Tanzania.
  • Oriyo N; Amana Regional Referral Hospital, Dar es Salaam, Tanzania.
  • Mghamba JM; National Institute for Medical Research, Headquarter, Dar es Salaam, Tanzania.
  • Fredrick A; National Institute for Medical Research, Headquarter, Dar es Salaam, Tanzania.
  • Ramaiya K; Ministry of Health, Community Development, Gender, Elderly and Children, Dodoma, Tanzania.
  • Zumla A; National Institute for Medical Research, Muhimbili Research Centre, Dar es Salaam, Tanzania.
  • Jaffar S; Hindu Mandal Hospital, Dar es Salaam, Tanzania.
  • Mfinanga SG; Center for Clinical Microbiology, Division of Infection and Immunity, University College London, Royal Free Hospital Campus, London, UK.
IJID Reg ; 2: 118-125, 2022 Mar.
Article in English | MEDLINE | ID: covidwho-1899808
ABSTRACT

Background:

A prospective cohort study of the clinical presentations and management outcomes of laboratory-confirmed COVID-19 patients in the early months of the pandemic was performed at two hospitals in Dar es Salaam, Tanzania.

Methods:

Between April 1 and May 31, 2020, laboratory-confirmed COVID-19 patients seen at two tertiary facilities were consecutively enrolled in the study and followed up for 21 days.

Results:

121 COVID-19 patients were enrolled; 112 (92.6%) were admitted while nine (7.4%) were seen as outpatients. The median (IQR) age of patients was 41 (30-54) years; 72 (59.5%) were male. The median (IQR) reported days from hospital admission to recovery and to death were 10 (6-18) and 5.5 (3-9), respectively. Forty-four (36.4%) patients had at least one underlying condition. Of the 112 admissions, 17 (15.2%) went to ICU, of whom 14 (82.3%) died. At the end of follow-up, 93 (76.9%) recovered, 18 (14.9%) died, seven (5.8%) remained asymptomatic, and one (0.8%) remained ill.

Conclusion:

Three-quarters of all COVID-19 patients were less than 60 years, reflecting Africa's young population . High ICU admissions and mortality were observed.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Cohort study / Observational study / Prognostic study Language: English Journal: IJID Reg Year: 2022 Document Type: Article Affiliation country: J.ijregi.2021.12.010

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Cohort study / Observational study / Prognostic study Language: English Journal: IJID Reg Year: 2022 Document Type: Article Affiliation country: J.ijregi.2021.12.010