Characterization of nanoparticles-based vaccines for COVID-19.
Nat Nanotechnol
; 17(6): 570-576, 2022 06.
Article
in English
| MEDLINE | ID: covidwho-1900493
ABSTRACT
Several vaccines against COVID-19 use nanoparticles to protect the antigen cargo (either proteins or nucleic acids), increase the immunogenicity and ultimately the efficacy. The characterization of these nanomedicines is challenging due to their intrinsic complexity and requires the use of multidisciplinary techniques and competencies. The accurate characterization of nanovaccines can be conceptualized as a combination of physicochemical, immunological and toxicological assays. This will help to address key challenges in the preclinical characterization, will guide the rapid development of safe and effective vaccines for current and future health crises, and will streamline the regulatory process.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Vaccines
/
Nanoparticles
/
COVID-19
Topics:
Vaccines
Limits:
Humans
Language:
English
Journal:
Nat Nanotechnol
Year:
2022
Document Type:
Article
Affiliation country:
S41565-022-01129-w
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