Molecular Elucidation and Therapeutic Targeting for Combating COVID-19: Current Scenario and Future Prospective.
Curr Mol Med
; 22(10): 894-907, 2022.
Article
in English
| MEDLINE | ID: covidwho-1902786
ABSTRACT
The coronavirus disease 2019 (COVID-19) is a contagious disease that is caused by a novel coronavirus. The human coronavirus (HCoV) is recognized as one of the most rapidly evolving viruses owing to its high genomic nucleotide substitution rates and recombination. Among the severe acute respiratory syndrome (SARS) and Middle- East respiratory syndrome (MERS), COVID-19 has spread more rapidly and increased the level of globalization and adaptation of the virus in every environmental condition due to their high rate of molecular diversity. The whole article highlights the general characteristics of coronavirus, their molecular diversity, and molecular protein targeting against COVID-19 with their newer approaches. Through this review, an attempt has been made to critically evaluate the recent advances and future aspects that are helpful to the treatment of COVID-19 based on the present understanding of SARS-CoV-2 infections, which may offer new insights and potential therapeutic targets for the treatment of COVID-19.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Middle East Respiratory Syndrome Coronavirus
/
COVID-19 Drug Treatment
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Curr Mol Med
Journal subject:
Molecular Biology
Year:
2022
Document Type:
Article
Affiliation country:
1566524021666210203113849
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