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COVID-19 Vaccines and the Efficacy of Currently Available Vaccines Against COVID-19 Variants.
Panneer Selvam, Suganya; Ramani, Pratibha; R, Ramya; Sundar, Sandhya; T A, Lakshmi.
  • Panneer Selvam S; Oral Pathology, Saveetha Dental College & Hospital, Chennai, IND.
  • Ramani P; Oral Pathology, Saveetha Dental College & Hospital, Chennai, IND.
  • R R; Oral Biology, Saveetha Dental College & Hospital, Chennai, IND.
  • Sundar S; Oral Pathology, Saveetha Dental College & Hospital, Chennai, IND.
  • T A L; Oral Pathology, Saveetha Dental College & Hospital, Chennai, IND.
Cureus ; 14(5): e24927, 2022 May.
Article in English | MEDLINE | ID: covidwho-1903866
ABSTRACT
Severe acute respiratory syndrome coronavirus 2 is the seventh member of the Coronaviridiae family of viruses, which are thought to be transmitted by Chinese horseshoe bats. The virus undergoes mutations leading to variants such as B.1.1.7 (alpha), B.1.351 (beta), P.1 (gamma), and B.1.617 (delta), as well as the recent variant B.1.1.529 (omicron), which has around 30 deletions, making it a severely mutated form that lowers vaccination-induced protection. Vaccine efficacy is usually expressed as relative risk reduction, which is based on the ratio of attack rates with and without a vaccine, whereas absolute risk reduction is based on the entire population. Rather than two doses, recent research suggests that a third dose/booster dose may aid in protection against future variants. The constant influx of mutant variations is putting a strain on vaccine production. Despite the challenges, we are optimistic that the epidemic will be eradicated by achieving mass immunity and by ensuring that everyone receives vaccines at a faster rate.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Topics: Vaccines / Variants Language: English Journal: Cureus Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Topics: Vaccines / Variants Language: English Journal: Cureus Year: 2022 Document Type: Article