Wildlife as a source of SARS-CoV-2 evolution
Pakistan Journal of Zoology
; 54(4):1899-1904, 2022.
Article
in English
| CAB Abstracts | ID: covidwho-1904009
ABSTRACT
Coronavirus consists of single-stranded, enveloped and RNA virus, largest genome among all RNA viruses and has 4 proteins i.e. envelope, spike, nucleocapsid and membrane. Coronaviruses are classified into 4 genera Alphacoronavirus, Betacoronavirus, Gammacoronavirus and Deltacoronavirus. Betacoronavirus most probably originated from bats and the virus may have jumped to avian species and evolved as Deltacoronavirus group. The avian coronaviruses jumped among other avian species, giving rise to Gammacoronavirus from Deltacoronavirus, while Betacoronavirus may have given rise to Alphacoronavirus. It is known that SARS-CoV-2 belongs to Betacoronavirus. This most similar virus is verified in bat and Malayan Pangolin. Analysis showed that SARS-CoV-2 most probably originated by recombination of both bat and pangolin viruses. Viral protein seroconversion and viral specific nucleotide positive documented in all COVID-19 patients tested provides confirmation of a link between the presence of this virus and the disease.
Prion, Viral, Bacterial and Fungal Pathogens of Humans [VV210]; Taxonomy and Evolution [ZZ380]; Genetics and Molecular Biology of Microorganisms [ZZ395]; Pathogens, Parasites and Infectious Diseases (Wild Animals) [YY700]; viral diseases; phylogeny; nucleocapsid proteins; recombination; seroconversion; viral proteins; wildlife; coronavirus disease 2019; Severe acute respiratory syndrome coronavirus 2; Chiroptera; RNA viruses; Alphacoronavirus; Betacoronavirus; Gammacoronavirus; Deltacoronavirus; Malaysia; Severe acute respiratory syndrome-related coronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; viruses; mammals; vertebrates; Chordata; animals; eukaryotes; APEC countries; ASEAN Countries; Commonwealth of Nations; South East Asia; Asia; upper-middle income countries; very high Human Development Index countries; Orthocoronavirinae; viral infections; SARS-CoV-2; genetic recombination
Full text:
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Collection:
Databases of international organizations
Database:
CAB Abstracts
Language:
English
Journal:
Pakistan Journal of Zoology
Year:
2022
Document Type:
Article
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