Comparison of pneumonia features in children caused by SARS-CoV-2 and other viral respiratory pathogens.
Pediatr Pulmonol
; 57(10): 2374-2382, 2022 10.
Article
in English
| MEDLINE | ID: covidwho-1905935
ABSTRACT
BACKGROUND:
Pneumonia is a frequent manifestation of coronavirus disease 2019 (COVID-19) in hospitalized children.METHODS:
The study involved 80 hospitals in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Spanish Pediatric National Cohort. Participants were children <18 years, hospitalized with SARS-CoV-2 community-acquired pneumonia (CAP). We compared the clinical and radiological characteristics of SARS-CoV-2-associated CAP with CAP due to other viral etiologies from ValsDance (retrospective) cohort.RESULTS:
In total, 151 children with SARS-CoV-2-associated CAP and 138 with other viral CAP were included. Main clinical features of SARS-CoV-2-associated CAP were cough, fever, or dyspnea. Lymphopenia was found in 43% patients and 15% required admission to the pediatric intensive care unit (PICU). Chest X-ray revealed condensation (42%) and other infiltrates (58%). Compared with CAP from other viral pathogens, COVID-19 patients were older, with lower C-reactive protein (CRP) levels, less wheezing, and greater need of mechanical ventilation (MV). There were no differences in the use of continuous positive airway pressure (CPAP) or HVF, or PICU admission between groups.CONCLUSION:
SARS-CoV-2-associated CAP in children presents differently to other virus-associated CAP children are older and rarely have wheezing or high CRP levels; they need less oxygen but more CPAP or MV. However, several features overlap and differentiating the etiology may be difficult. The overall prognosis is good.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Community-Acquired Infections
/
COVID-19
Type of study:
Cohort study
/
Etiology study
/
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Topics:
Long Covid
Limits:
Child
/
Humans
Language:
English
Journal:
Pediatr Pulmonol
Journal subject:
Pediatrics
Year:
2022
Document Type:
Article
Affiliation country:
Ppul.26042
Similar
MEDLINE
...
LILACS
LIS