Herd immunity under individual variation and reinfection.
J Math Biol
; 85(1): 2, 2022 06 30.
Article
in English
| MEDLINE | ID: covidwho-1906031
ABSTRACT
We study a susceptible-exposed-infected-recovered (SEIR) model considered by Aguas et al. (In Herd immunity thresholds for SARS-CoV-2 estimated from unfolding epidemics, 2021), Gomes et al. (In J Theor Biol. 540111063, 2022) where individuals are assumed to differ in their susceptibility or exposure to infection. Under this heterogeneity assumption, epidemic growth is effectively suppressed when the percentage of the population having acquired immunity surpasses a critical level - the herd immunity threshold - that is lower than in homogeneous populations. We derive explicit formulas to calculate herd immunity thresholds and stable configurations, especially when susceptibility or exposure are gamma distributed, and explore extensions of the model.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Epidemics
/
COVID-19
Type of study:
Observational study
Limits:
Humans
Language:
English
Journal:
J Math Biol
Year:
2022
Document Type:
Article
Affiliation country:
S00285-022-01771-x
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